ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019
Sex differences in blood pressure regulation during ischemic isometric exercise: the role of the β-adrenergic receptors.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Sex differences in beat-to-beat blood pressure variability following isometric handgrip exercise.European journal of applied physiology · 2026Trial
- Effect of Exercise Modalities on Post-Exercise Hypotension in Normotensive Postmenopausal Women: A Randomized Controlled Trial on Vasomotor Symptoms Influence.European journal of sport science · 2025Trial
- Short-term water deprivation attenuates the exercise pressor reflex in older female adults.Physiological reports · 2020Trial
- Sex Differences in Intraocular Pressure and Retinal Vessel Responses After Sustained Isometric Knee Extension in Young Adults: A Quasi-Experimental Study.Journal of clinical medicine · 2026Article
- The effect of sex on the isolated and combined α- and β-adrenergic control of blood flow during handgrip in adults at high altitude: An exploratory study.Physiological reports · 2026Article
- Novel Advances in Our Understanding of Sex-Dependent Control of Blood Pressure.Annual review of physiology · 2026Review
- Efficacy and moderators of isometric resistance training (IRT) on resting blood pressure among patients with pre- to established hypertension: a multilevel meta-review and regression analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Role of ENaC in gender-associated differences in blood pressure.Iranian journal of basic medical sciences · 2025Article
- Influence of endogenous and exogenous hormones on the cardiovascular response to lower extremity exercise and group III/IV activation in young females.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Peak systolic blood pressure during preparticipation exercise testing in 12,083 athletes: age, sex, and workload-indexed values and predictors.Frontiers in physiology · 2024Article
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- Adjusting for muscle strength and body size attenuates sex differences in the exercise pressor reflex in young adults.American journal of physiology. Heart and circulatory physiology · 2023Article
- Spontaneous baroreflex sensitivity is attenuated in male UCD-type 2 diabetes mellitus rats: A link between metabolic and autonomic dysfunction.Autonomic neuroscience : basic & clinical · 2023Article
- Age-related alterations in the cardiovascular responses to acute exercise in males and females: role of the exercise pressor reflex.Frontiers in physiology · 2023Review
- Adrenergic Modulation of Erythropoiesis After Trauma.Frontiers in physiology · 2022Review
- Sex differences in workload-indexed blood pressure response and vascular function among professional athletes and their utility for clinical exercise testing.European journal of applied physiology · 2021Article
- Blood Pressure Response and Vascular Function of Professional Athletes and Controls.Sports medicine international open · 2021Article
- Sex Differences in Exercise-Training-Related Functional and Morphological Adaptation of Rat Gracilis Muscle Arterioles.Frontiers in physiology · 2021Article
- Sex differences in muscle activity emerge during sustained low-intensity contractions but not during intermittent low-intensity contractions.Physiological reports · 2020Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We sought to investigate whether the β-adrenergic receptors play a pivotal role in sex-related differences in arterial blood pressure (BP) regulation during isometric exercise. Sixteen volunteers (8 women) performed 2 min of ischemic isometric handgrip exercise (IHE) and 2 min of postexercise circulatory occlusion (PECO). Heart rate (HR) and beat-to-beat arterial BP were continuously measured. Beat-to-beat estimates of stroke volume (ModelFlow) were obtained and matched with HR to calculate cardiac output (Q̇) and total peripheral resistance (TPR). Two trials were randomly conducted between placebo and nonselective β-adrenergic blockade (40 mg propranolol). Under the placebo condition, the magnitude of the BP response in IHE was lower in women compared with men. During PECO, the BP remained elevated and the sex differences persisted. The β-blockade attenuated the BP response during IHE in men (∆57 ± 4 vs. ∆45 ± 7 mmHg,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.