Evidence map›Paper›PMID 31219767›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Serum IL-6 and sIL-6R in type 2 diabetes contribute to impaired capillary-like network formation.

Rian Q Landers-Ramos, Jacob B Blumenthal, Steven J Prior

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Diabetic Lung Can Be Ameliorated byEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rian Q Landers-RamosDepartment of Kinesiology, Towson University, Towson, Maryland.
Jacob B BlumenthalDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Steven J PriorDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.ORCID 0000-0002-4627-6489
University of Maryland, Baltimore · US

Funding

Vascular Biology Training ProgramT32HL007698 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Rosemary A Kozar, Dudley K. Strickland · 1991 to 2026
$8.7M
Effects of Aerobic Exerise on EPCs and Vascular Dysfunction in Aging and T2DMK23AG040775 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI PRIOR, STEVEN J · 2012 to 2014
$532k
CSRD VA I01 CX000730NHLBI NIH HHS T32 HL007698NIA NIH HHS K23 AG040775
6 · The paper itself

Abstract

We hypothesized that the serum from individuals with type 2 diabetes mellitus (T2DM) and impaired glucose tolerance (IGT) would reduce in vitro capillary-like network formation compared with normal glucose tolerance (NGT) serum and that this would occur along with higher serum concentrations of inflammatory cytokines and lower concentrations of angiogenic growth factors. Subjects were sedentary, older (55-65 yr) adults with NGT, IGT, or T2DM (

Indexed as

AgedBlood GlucoseBody Mass IndexCapillariesDiabetes Mellitus, Type 2Endothelial CellsFemaleGlucose IntoleranceGlucose Tolerance TestHumansInterleukin-6MaleMiddle AgedReceptors, Interleukin-6Blood GlucoseIL6 protein, humanIL6R protein, humanInterleukin-6Receptors, Interleukin-6angiogenesiscytokinesdiabetes mellitusIL-6impaired glucose tolerance

Identifiers

PMID31219767
PMCPMC6732435
OpenAlexW2952264412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.