ArticleCerebral cortex (New York, N.Y. : 1991)2020
Translating Fear Circuitry: Amygdala Projections to Subgenual and Perigenual Anterior Cingulate in the Macaque.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed.
- Transcriptional and functional profiles of muscarinic receptor-expressing neurons in primate lateral prefrontal and anterior cingulate cortices.Communications biology · 2026Article
- Circuit-Based Approaches to Understanding the Anterior Cingulate Cortex (ACC).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry.Cell reports · 2025Article
- Collateralization patterns of principal basolateral amygdala neurons delineate distinct output streams.iScience · 2025Article
- Chemogenetic inhibition of amygdala to ventrolateral prefrontal cortex communication selectively impacts contingent learning.bioRxiv : the preprint server for biology · 2025Article
- Brain-wide connections of the parvicellular subdivision of the basolateral and basomedial amygdaloid nuclei in the rats.Frontiers in neural circuits · 2025Article
- Translation of monosynaptic circuits underlying amygdala fMRI neurofeedback training.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Anatomy and connectivity of the Göttingen minipig subgenual cortex (Brodmann area 25 homologue).Brain structure & function · 2024Article
- Differential functional organization of amygdala-medial prefrontal cortex networks in macaque and human.Communications biology · 2024Article
- Pathophysiology in cortico-amygdala circuits and excessive aversion processing: the role of oligodendrocytes and myelination.Brain communications · 2024Review
- Single basolateral amygdala neurons in macaques exhibit distinct connectional motifs with frontal cortex.Neuron · 2023Article
- Subgenual and Hippocampal Pathways in Amygdala Are Set to Balance Affect and Context Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The Aversive Lens: Stress effects on the prefrontal-cingulate cortical pathways that regulate emotion.Neuroscience and biobehavioral reviews · 2023Review
- Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques.Current research in neurobiology · 2023Review
- Article
- Altered Development of Amygdala-Connected Brain Regions in Males and Females with Autism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Cortical Granularity Shapes the Organization of Afferent Paths to the Amygdala and Its Striatal Targets in Nonhuman Primate.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia.Frontiers in systems neuroscience · 2022Review
- Childhood Threat Is Associated With Lower Resting-State Connectivity Within a Central Visceral Network.Frontiers in psychology · 2022Article
- The prefrontal cortex, pathological anxiety, and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Rodent fear-learning models posit that amygdala-infralimbic connections facilitate extinction while amygdala-prelimbic prefrontal connections mediate fear expression. Analogous amygdala-prefrontal circuitry between rodents and primates is not established. Using paired small volumes of neural tracers injected into the perigenual anterior cingulate cortex (pgACC; areas 24b and 32; a potential homologue to rodent prelimbic cortex) and subgenual anterior cingulate cortex (sgACC, areas 25 and 14c; a potential homologue to rodent infralimbic cortex) in a single hemisphere, we mapped amygdala projections to the pgACC and sgACC within single subjects. All injections resulted in dense retrograde labeling specifically within the intermediate division of the basal nucleus (Bi) and the magnocellular division of the accessory basal nucleus (ABmc). Areal analysis revealed a bias for connectivity with the sgACC, with the ABmc showing a greater bias than the Bi. Double fluorescence analysis revealed that sgACC and pgACC projections were intermingled within the Bi and ABmc, where a proportion were double labeled. We conclude that amygdala inputs to the ACC largely originate from the Bi and ABmc, preferentially connect to the sgACC, and that a subset collaterally project to both sgACC and pgACC. These findings advance our understanding of fear extinction and fear expression circuitry across species.
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