Evidence map›Paper›PMID 31219399›Full record

ArticlePrion2019

Clinicopathological findings of an MM2-cortical-type sporadic Creutzfeldt-Jakob disease patient with cortical blindness during a course of glaucoma and age-related macular degeneration.

Yuichi Hayashi, Yasushi Iwasaki, Masahiro Waza, Hideaki Shibata, Akio Akagi, Akio Kimura, Takashi Inuzuka, Katsuya Satoh, Tetsuyuki Kitamoto, Mari Yoshida and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Prion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Yuichi Hayashia Department of Neurology , Gifu University Graduate School of Medicine , Gifu , Japan.ORCID 0000-0003-4048-3513
Yasushi Iwasakib Autopsy Center of Prion Disease , Institute for Medical Sciences of Aging, Aichi Medical University , Nagakute , Japan.ORCID 0000-0002-0059-3104
Masahiro Wazac Department of Neurology , Kakamigahara Rehabilitation Hospital , Kakamigahara , Japan.ORCID 0000-0002-1582-4745
Hideaki Shibataa Department of Neurology , Gifu University Graduate School of Medicine , Gifu , Japan.
Akio Akagib Autopsy Center of Prion Disease , Institute for Medical Sciences of Aging, Aichi Medical University , Nagakute , Japan.
Akio Kimuraa Department of Neurology , Gifu University Graduate School of Medicine , Gifu , Japan.
Takashi Inuzukaa Department of Neurology , Gifu University Graduate School of Medicine , Gifu , Japan.
Katsuya Satohe Department of Locomotive Rehabilitation Sciences , Nagasaki University Graduate School of Medicine , Nagasaki , Japan.
Tetsuyuki Kitamotof Division of CJD Science and Technology, Department of Prion Research , Center for Translational and Advanced Animal Research on Human Diseases, Tohoku University School of Medicine , Sendai , Japan.
Mari Yoshidab Autopsy Center of Prion Disease , Institute for Medical Sciences of Aging, Aichi Medical University , Nagakute , Japan.
Takayoshi Shimohataa Department of Neurology , Gifu University Graduate School of Medicine , Gifu , Japan.ORCID 0000-0002-8788-9089
Gifu University · JPAichi Medical University · JPGifu Municipal Hospital · JPNagasaki University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report an autopsy-verified patient with MM2-coritical-type sporadic Creutzfeldt-Jakob disease (MM2C-type sCJD) presenting cortical blindness during a course of glaucoma and age-related macular degeneration, and focus on the difficulties involved in early clinical diagnosis. An 83-year-old man was admitted to our hospital 15 months after the onset of cortical blindness, and 9 months after the onset of progressive dementia. Neurological examination revealed dementia, frontal signs, visual disturbance, dysphagia, myoclonus and exaggerated tendon reflexes in the four extremities. Diffusion-weighted MRI (DW-MRI) showed cortical hyperintensities predominantly in the bilateral occipital lobes.

Indexed as

Aged, 80 and overBlindness, CorticalBrainCreutzfeldt-Jakob SyndromeGlaucomaHumansMacular DegenerationMalePrionsPrionscortical blindnessCreutzfeldt-Jakob diseasedementiadiffusion-weighted MRIelderly patientMM2-cortical-type sporadic Creutzfeldt-Jakob diseaseocular disease

Identifiers

PMID31219399
PMCPMC6629179
OpenAlexW2952409647

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.