Evidence map›Paper›PMID 31219348›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from

Alessio Nocentini, Sameh M Osman, Igor A Almeida, Veronica Cardoso, Fatmah Ali S Alasmary, Zeid AlOthman, Alane B Vermelho, Paola Gratteri, Claudiu T Supuran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Inhibition studies of the protozoan α-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  5. Activation of the β-carbonic anhydrase from the protozoan pathogenJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  6. Article
  7. Article
  8. Coumarin carbonic anhydrase inhibitors from natural sources.Journal of enzyme inhibition and medicinal chemistry · 2020
    Review
  9. Article
  10. Article
  11. International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessio Nocentinia Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Sesto Fiorentino , Italy.
Sameh M Osmanb Department of Chemistry, College of Science , King Saud University , Riyadh , Saudi Arabia.
Igor A Almeidac Department of Natural Products and Food, School of Pharmacy , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.
Veronica Cardosod BIOINOVAR - Biotechnology Laboratories: Biocatalysis, Bioproducts and Bioenergy, Institute of Microbiology Paulo de Góes , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.
Fatmah Ali S Alasmaryb Department of Chemistry, College of Science , King Saud University , Riyadh , Saudi Arabia.
Zeid AlOthmanb Department of Chemistry, College of Science , King Saud University , Riyadh , Saudi Arabia.
Alane B Vermelhod BIOINOVAR - Biotechnology Laboratories: Biocatalysis, Bioproducts and Bioenergy, Institute of Microbiology Paulo de Góes , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.ORCID http://orcid.org/0000-0001-5926-4172
Paola Gratteria Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Sesto Fiorentino , Italy.
Claudiu T Supurana Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Sesto Fiorentino , Italy.ORCID http://orcid.org/0000-0003-4262-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease and leishmaniasis are neglected tropical disorders caused by the protozoans

Indexed as

Antiprotozoal AgentsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesDose-Response Relationship, DrugHumansIsoenzymesLeishmania donovaniMolecular StructureParasitic Sensitivity TestsStructure-Activity RelationshipTrypanosoma cruziAntiprotozoal AgentsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesIsoenzymesCarbonic anhydraseChagas diseasenitroaromatics

Identifiers

PMID31219348
PMCPMC6598531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.