Evidence map›Paper›PMID 31219085›Full record

ArticleThe Indian journal of medical research2019

Molecular characterization of extended-spectrum β-lactamases among clinical isolates of

Vikas Gautam, Anjana Thakur, Megha Sharma, Avinash Singh, Shruti Bansal, Aditi Sharma, Arti Kapil, Bimal Kumar Das, Sujatha Sistla, Subhash Chandra Parija and 5 more

Open access · diamondAbstract read
In one paragraph

Article in The Indian journal of medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Klebsiella pneumoniae: an increasing threat to public health.Annals of clinical microbiology and antimicrobials · 2020
    Pooled it
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  11. Molecular Characterization ofInfection and drug resistance · 2022
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  12. Distribution ofInfection and drug resistance · 2022
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  13. Study on the drug resistance and pathogenicity ofFrontiers in microbiology · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Whole Genome Sequencing of PediatricFrontiers in microbiology · 2021
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Vikas GautamDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Anjana ThakurDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Megha SharmaDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Avinash SinghDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Shruti BansalDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Aditi SharmaDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Arti KapilDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Bimal Kumar DasDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Sujatha SistlaDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
Subhash Chandra ParijaDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
Balaji VeeraraghavanDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
John Antony Jude PrakashDepartment of Clinical Microbiology, Christian Medical College, Vellore, India.
Kamini WaliaDivision of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
V C OhriDivision of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Pallab RayDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INAll India Institute of Medical Sciences · INChristian Medical College & Hospital · INIndian Council of Medical Research · INJawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & objectives: The increasing prevalence of extended-spectrum β-lactamases (ESBLs) has abated therapeutic options worldwide. This study was undertaken to investigate the molecular profile and resistance patterns of ESBLs among clinical isolates of Escherichia coli and Klebsiella pneumoniae at four tertiary care centres in India. Methods: Clinical isolates of E. coli and K. pneumoniae were collected from the All India Institute of Medical Sciences (AIIMS), New Delhi; the Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry; Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh and Christian Medical College (CMC), Vellore, over one and a half year period. Antimicrobial susceptibility was determined by Kirby-Bauer disc diffusion method. ESBLs were confirmed phenotypically, and multiplex PCR was performed to identify genes for β-lactamases (bla Results: Among 341 E. coli isolates collected during the study period, 171 (50%) harboured bla Interpretation & conclusions: The prevalence of ESBL among four study centres varied, and bla

Indexed as

beta-LactamasesCarbapenemsDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsGenotypeHumansIndiaKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsTertiary Care Centersbeta-LactamasesCarbapenemsAntibiotic sensitivitycolistin resistanceEscherichia coliextended-spectrum βKlebsiella pneumoniaelactamases

Identifiers

PMID31219085
PMCPMC6563744
OpenAlexW2948031886

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.