ArticleMolecular plant pathology2019
The type III effector RipB from Ralstonia solanacearum RS1000 acts as a major avirulence factor in Nicotiana benthamiana and other Nicotiana species.
Article in Molecular plant pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed.
- Pathogenicity and virulence ofVirulence · 2026Review
- ThePlants (Basel, Switzerland) · 2026Article
- Multiple effectors trigger non-host resistance in Solanum americanum against Pseudomonas syringae.The Plant journal : for cell and molecular biology · 2025Article
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- Molecular Dialog ofInternational journal of molecular sciences · 2025Review
- Targeting effector proteins of plant pathogens as a strategy for durable plant disease resistance.Frontiers in microbiology · 2025Article
- A single NLR gene confers resistance to leaf and stripe rust in wheat.Nature communications · 2024Article
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- Efficacy of 2,4-Di-ACS omega · 2024Article
- TheInternational journal of molecular sciences · 2023Article
- A plasma membrane nucleotide-binding leucine-rich repeat receptor mediates the recognition of the Ralstonia pseudosolanacearum effector RipY in Nicotiana benthamiana.Plant communications · 2023Article
- The Ralstonia pseudosolanacearum effector RipE1 is recognized at the plasma membrane by NbPtr1, the Nicotiana benthamiana homologue of Pseudomonas tomato race 1.Molecular plant pathology · 2023Article
- Phosphatidylinositol-phospholipase C3 negatively regulates the hypersensitive response via complex signaling with MAP kinase, phytohormones, and reactive oxygen species in Nicotiana benthamiana.Journal of experimental botany · 2023Article
- Phosphatidylinositol-phospholipase C4 suppresses the hypersensitive response ofPlant biotechnology (Tokyo, Japan) · 2023Article
- Ubiquitin E3 ligase activity ofFrontiers in microbiology · 2023Article
- Proposal to classifyFrontiers in microbiology · 2023Article
- Comparative genomic analysis ofFrontiers in plant science · 2023Article
- Article
- Fungal Effectoromics: A World in Constant Evolution.International journal of molecular sciences · 2022Review
- Microbial Effectors: Key Determinants in Plant Health and Disease.Microorganisms · 2022Review
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Abstract
Ralstonia solanacearum is the causal agent of bacterial wilt in solanaceous crops. This pathogen injects approximately 70 effector proteins into plant cells via the Hrp type III secretion system in an early stage of infection. To identify an as-yet-unidentified avirulence factor possessed by the Japanese tobacco-avirulent strain RS1000, we transiently expressed RS1000 effectors in Nicotiana benthamiana leaves and monitored their ability to induce effector-triggered immunity (ETI). The expression of RipB strongly induced the production of reactive oxygen species and the expressions of defence-related genes in N. benthamiana. The ripB mutant of RS1002, a nalixidic acid-resistant derivative of RS1000, caused wilting symptoms in N. benthamiana. A pathogenicity test using R. solanacearum mutants revealed that the two already known avirulence factors RipP1 and RipAA contribute in part to the avirulence of RS1002 in N. benthamiana. The Japanese tobacco-virulent strain BK1002 contains mutations in ripB and expresses a C-terminal-truncated RipB that lost the ability to induce ETI in N. benthamiana, indicating a fine-tuning of the pathogen effector repertoire to evade plant recognition. RipB shares homology with Xanthomonas XopQ, which is recognized by the resistance protein Roq1. The RipB-induced resistance against R. solanacearum was abolished in Roq1-silenced plants. These findings indicate that RipB acts as a major avirulence factor in N. benthamiana and that Roq1 is involved in the recognition of RipB.
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