Evidence map›Paper›PMID 31218544›Full record

ArticleProbiotics and antimicrobial proteins2020

In Vivo Implications of Potential Probiotic Lactobacillus reuteri LR6 on the Gut and Immunological Parameters as an Adjuvant Against Protein Energy Malnutrition.

Sheenam Garg, Tejinder P Singh, Ravinder K Malik

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Limosilactobacillus reuteri UN41 improves the survival rate and exhibits hepatoprotective effects in a murine model of Salmonella infection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Frontiers in cellular and infection microbiology · 2023
    Review
  10. Frontiers in immunology · 2023
    Review
  11. The role of potential probiotic strainsFrontiers in microbiology · 2023
    Review
  12. Review
  13. Review
  14. Impact of Heat-KilledNutrients · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sheenam GargDairy Microbiology Division, National Dairy Research Institute, Karnal, 132001, India. sheenam25garg@gmail.com.
Tejinder P SinghDairy Microbiology Department, College of Dairy Science and Technology, Lala Lajpat Rai University of Veterinary and Animal Science, Hisar, 125004, India.
Ravinder K MalikDairy Microbiology Division, National Dairy Research Institute, Karnal, 132001, India.
National Dairy Research Institute · INLala Lajpat Rai University of Veterinary and Animal Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigated the impact of probiotic Lactobacillus reuteri LR6 on the gut and systemic immunity using protein energy malnourished (PEM) murine model. Thirty male Swiss albino mice were divided into five groups: control (C), malnourished (M), probiotic fermented milk (PFM), skim milk (SM), and bacterial suspension (BS) with six mice per group. Group C was fed with conventional diet throughout the study while the other groups were fed with protein calorie restricted diet until the development of malnutrition. After development of malnutrition, group M was continued with the restricted diet while other groups were fed with re-nourished diet supplemented with PFM, SM, and BS for 1 week, respectively. Thereafter, mice were sacrificed and different histological, microbiological, and immunological parameters were studied. Probiotics feeding in PEM model as fermented product or bacterial suspension improved the intestinal health in terms of intact morphology of colonic crypts, normal goblet cells, and intact lamina propria with no inflammation in large intestine, absence of fibrosis, and no inflammation in spleen. The number of secretory IgA

Indexed as

Gastrointestinal MicrobiomeLimosilactobacillus reuteriAnimalsIntestinal MucosaMaleMiceProbioticsProtein-Energy MalnutritionGut microbiota changesImmunocytochemistryLactobacillus reuteriProbioticsProtein energy malnutrition

Identifiers

PMID31218544
OpenAlexW2951190748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.