Evidence map›Paper›PMID 31218247›Full record

ArticleRegenerative engineering and translational medicine2019

The Maturation of Tissue-Engineered Skeletal Muscle Units following 28-Day Ectopic Implantation in a Rat.

Brittany L Rodriguez, Shelby E Florida, Keith W VanDusen, Brian C Syverud, Lisa M Larkin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative engineering and translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brittany L RodriguezDepartment of Biomedical Engineering, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Shelby E FloridaDepartment of Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Keith W VanDusenDepartment of Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Brian C SyverudDepartment of Biomedical Engineering, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Lisa M LarkinDepartment of Biomedical Engineering, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.

Funding

Utilization of Engineered Skeletal Muscle Units to Repair Volumetric MuscleR01AR067744 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LARKIN, LISA M · 2015 to 2019
$2.3M
NIAMS NIH HHS R01 AR067744
6 · The paper itself

Abstract

Volumetric muscle loss (VML) is a loss of skeletal muscle that results in a sustained impairment of function and is often accompanied by physical deformity. To address the need for more innovative repair options, our laboratory has developed scaffold-free, multiphasic tissue-engineered skeletal muscle units (SMUs) to treat VML injuries. In our previous work, using the concept of the "body as a bioreactor", we have shown that implantation promotes the maturation of our SMUs beyond what is possible

Indexed as

implantationsatellite cellscaffold-freeskeletal muscletissue engineering

Identifiers

PMID31218247
PMCPMC6583911

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.