SynthesisBioMed research international2019
The Impact of Steatosis on the Outcome of Liver Transplantation: A Meta-Analysis.
Synthesis in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ex vivo machine perfusion: current applications and future directions in liver transplantation.Langenbeck's archives of surgery · 2021Pooled it
- iTRAQ- and MRM-Based Proteomics Identify Early Injury Biomarkers for Primary Dysfunction After Liver Transplantation.Annals of transplantation · 2026Article
- Inferior Long-Term Outcome of Fatty Liver Allografts After Orthotopic Liver Transplantation.Annals of transplantation · 2026Article
- Standardized evaluation protocols for deceased and living liver donors: a practical framework for emerging liver transplant programs.Frontiers in transplantation · 2026Review
- Pediatric liver transplant outcomes: A comparative analysis of steatotic donor grafts.Journal of pediatric gastroenterology and nutrition · 2025Article
- Impact of Preoperative Treatment on Donor Hepatic Steatosis in Living Donor Liver Transplantation.Annals of transplantation · 2025Article
- The association between deceased donor body mass index and liver steatosis, fibrosis, portal infiltrates and patients' prognosis: a retrospective cohort study.Translational gastroenterology and hepatology · 2025Article
- Comparing Different Methods for the Diagnosis of Liver Steatosis: What Are the Best Diagnostic Tools?Diagnostics (Basel, Switzerland) · 2024Article
- Abnormal Liver Biopsies of Donor Grafts in Pediatric Liver Transplantation: How Do They Fare?Annals of transplantation · 2024Article
- CT-Based Hounsfield Units for Pre-donation Liver Steatosis Assessment: Enhancing Transplant Outcomes and Efficiency.Cureus · 2024Article
- Exosomes derived from bone marrow mesenchymal stem cells alleviate biliary ischemia reperfusion injury in fatty liver transplantation by inhibiting ferroptosis.Molecular and cellular biochemistry · 2024Article
- Development of a portable device to quantify hepatic steatosis in potential donor livers.Frontiers in transplantation · 2023Article
- Liver transplantation in the era of non-alcoholic fatty liver disease/metabolic (dysfunction) associated fatty liver disease: the dilemma of the steatotic liver graft on transplantation and recipient survival.Hepatobiliary surgery and nutrition · 2022Article
- Hepatic macrosteatosis in the US pediatric deceased liver donor population.Pediatric transplantation · 2022Article
- Changes in Indices of Steatosis and Fibrosis in Liver Grafts of Living Donors After Weight Reduction.Frontiers in surgery · 2022Article
- The impact of liver steatosis on the postoperative evolution after right lobe living-donor hepatectomy.Medicine and pharmacy reports · 2021Article
- Non-invasive real-time assessment of hepatic macrovesicular steatosis in liver donors: Hypothesis, design and proof-of-concept study.World journal of hepatology · 2021Review
- Application of ischaemia-free liver transplantation improves prognosis of patients with steatotic donor livers - a retrospective study.Transplant international : official journal of the European Society for Organ Transplantation · 2021Article
- Hepatic connective tissue growth factor expression and regulation differ between non-steatotic and non-alcoholic steatotic livers from brain-dead donor.Scientific reports · 2021Article
- Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsLiver transplantation is one of the most effective treatments for end-stage liver disease as well as for cases of acute liver failure. Facing organ donor shortage, liver transplant teams had to use marginal organs. Thus, increasing availability is a key concern of donor liver grafts including steatotic livers. However, the use of steatotic liver is still controversial. The aim of this systematic review and meta-analysis was to analyze the impact of steatosis on the outcome of liver transplantation.
methodsWe searched PubMed, Cochrane Library, Embase, Web of knowledge, and so on for studies published through May 31, 2018, in which patients experienced liver transplantation using fatty liver. All studies extracted outcome indicators, and we draw conclusions by contrasting outcome indicators in different groups of steatosis. Odds ratios and 95% confidence intervals were calculated. P<0.05 was considered as statistically significant difference.
results19 publications were included. There was no significant difference between the group of no steatosis and mild group in primary nonfunction rate (P=0.605) or early graft dysfunction rate (P=0.44). The PNF rate was significantly higher in moderate group (P=0.003) and severe group (P <0.001) compared with that in no steatosis group. The same results were seen in early graft dysfunction rate. However, graft survival rate and patient survival rate did not differ between groups.
conclusionsLivers with mild steatosis, even with moderate or severe steatosis, could be suitable donor under strict control of transplant conditions.
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