ArticleJournal of global health2019
Prevalence and correlates of chronic obstructive pulmonary disease and chronic respiratory symptoms in rural southwestern Uganda: a cross-sectional, population-based study.
Article in Journal of global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05223114 (Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Effect of HIV on respiratory symptoms, health status, and exertional capacity.AIDS (London, England) · 2025Pooled it
- Effect of Human Immunodeficiency Virus on Lung Function and Structure: A Systematic Review and Meta-Analysis.Annals of the American Thoracic Society · 2025Pooled it
- Chronic obstructive pulmonary disease in East Africa: a systematic review and meta-analysis.International health · 2024Pooled it
- Chronic obstructive pulmonary disease in sub-Saharan Africa.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022Pooled it
- Prevalence of abnormal spirometry and correlates of lung function decline among a population in rural Uganda.Journal of global health · 2026Article
- Lung function across the life course in Kenya: a series of cross-sectional surveys.ERJ open research · 2026Article
- Global disparities in chronic dyspnoea prevalence in population-based studies: a comprehensive literature review.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Personal PM2.5 exposure and lung function among adults with and without HIV who have recovered from pneumonia in Kampala, Uganda.Annals of the American Thoracic Society · 2026Article
- Susceptibility Patterns and Factors Associated with Multidrug Antibiotic Resistance Among Patients with Productive Cough in Southwestern Uganda.Infection and drug resistance · 2026Article
- HIV status is linked to higher odds of persistent respiratory symptoms in Tanzania: a longitudinal analysis.IJTLD open · 2025Article
- Article
- Population Prevalence and Correlates of Syphilis in Rural, Southwestern Uganda.Open forum infectious diseases · 2025Article
- Household air pollution and respiratory health in Africa: persistent risk and unchanged health burdens.Current opinion in pulmonary medicine · 2025Review
- Prevalence and factors associated with respiratory symptoms in an urban population: findings from BOLD study in Karachi, Pakistan.Discover medicine · 2025Article
- Chronic obstructive pulmonary disease burden, grades and erythrocytosis at a tertiary hospital in western Uganda.BMC pulmonary medicine · 2024Article
- Prevalence and Associated Factors of Chronic Obstructive Pulmonary Disease Among Adults in Neno District, Malawi: A Cross-Sectional Analytical Study.International journal of chronic obstructive pulmonary disease · 2024Article
- Burden and risk factors of chronic obstructive pulmonary disease in Sub-Saharan African countries, 1990-2019: a systematic analysis for the Global Burden of disease study 2019.EClinicalMedicine · 2023Article
- Chronic Obstructive Pulmonary Disease in Cameroon: Prevalence and Predictors-A Multisetting Community-Based Study.Pulmonary medicine · 2023Article
- Lung function and atherosclerosis: a cross-sectional study of multimorbidity in rural Uganda.BMC pulmonary medicine · 2022Observational
- Estimating the prevalence of COPD in an African country: evidence from southern Nigeria.Journal of global health reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe global burden of chronic obstructive pulmonary disease (COPD) disproportionately affects resource-limited settings such as sub-Saharan Africa (SSA), but population-based prevalence estimates in SSA are rare. We aimed to estimate the population prevalence of COPD and chronic respiratory symptoms in rural southwestern Uganda.
methodsAdults at least 18 years of age who participated in a population-wide census in rural southwestern Uganda completed respiratory questionnaires and lung function testing with bronchodilator challenge at health screening events in June 2015. We defined COPD as post-bronchodilator forced expiratory volume in one second to forced vital capacity ratio less than the lower limit of normal. We fit multivariable linear and log binomial regression models to estimate correlates of abnormal lung function and respiratory symptoms, respectively. We included inverse probability of sampling weights in models to facilitate population-level estimates.
resultsForty-six percent of census participants (843/1814) completed respiratory questionnaires and spirometry, of which 565 (67%) met acceptability standards. COPD and respiratory symptom population prevalence were 2% (95% confidence interval (CI) = 1%-3%) and 30% (95% CI = 25%-36%), respectively. Respiratory symptoms were more prevalent and lung function was lower among women and ever-smokers (
conclusionsCOPD population prevalence was low despite prevalent respiratory symptoms. This work adds to the growing body of literature depicting lower-than-expected COPD prevalence estimates in SSA and raises questions about whether the high respiratory symptom burden in rural southwestern Uganda represents underlying structural lung disease not identified by screening spirometry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.