ArticleAmerican journal of translational research2019
The in vivo chondrogenesis of cartilage stem/progenitor cells from auricular cartilage and the perichondrium.
Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
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Who cites it
11 citing papers in PubMed.
- ChondrocytesFrontiers in cell and developmental biology · 2026Review
- Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction.Bioactive materials · 2025Article
- Decellularized apple hypanthium as a plant-based biomaterial for cartilage regeneration in vitro: a comparative study of progenitor cell types and environmental conditions.Journal of biological engineering · 2025Article
- 3D printing tissue-engineered scaffolds for auricular reconstruction.Materials today. Bio · 2024Review
- The application and progress of stem cells in auricular cartilage regeneration: a systematic review.Frontiers in cell and developmental biology · 2023Review
- Article
- Review
- Comparative study of alginate and type I collagen as biomaterials for cartilage stem/progenitor cells to construct tissue-engineered cartilageFrontiers in bioengineering and biotechnology · 2022Article
- Long-Term Tri-Modal In Vivo Tracking of Engrafted Cartilage-Derived Stem/Progenitor Cells Based on Upconversion Nanoparticles.Biomolecules · 2021Article
- Biofabrication of a shape-stable auricular structure for the reconstruction of ear deformities.Materials today. Bio · 2021Article
- Effect of tissue expansion on chondrocyte sheets in cartilage composite reconstruction.American journal of translational research · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone marrow-derived stem cells are commonly studied for cartilage tissue engineering and regeneration medicine applications, but their ossification tendency and their limited capacity for chondrogenic differentiation depending on the donor age limit their clinical application. Cartilage stem/progenitor cells are ideal seeding cells, as cartilage stem/progenitor cells from auricular cartilage and the perichondrium have the inherent advantages of chondrogenesis capacity and an easy and nontraumatic harvesting process, displaying promise for applications. The identification and comparison of cartilage stem/progenitor cells from auricular cartilage and the perichondrium in vitro were explored in our previous study, but the in vivo chondrogenesis of these cells has not been fully examined. In the current study, we explored the ectopic chondrogenesis of cartilage stem progenitor/cells from auricular cartilage and the perichondrium after chondrogenic induction in vitro. Our results suggest that stem/progenitor cells from auricular cartilage exhibit significantly better chondrogenesis than those from the perichondrium in vivo, with upregulated chondrogenic genes and a stable cartilage phenotype, as well as good mechanical properties, indicating that stem/progenitor cells from auricular cartilage could be one type of ideal seeding cells for cartilage tissue engineering.
Indexed as
Identifiers
31217859PMC6556626What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.