Evidence map›Paper›PMID 31217852›Full record

ArticleAmerican journal of translational research2019

P2Y

Changjiang Lei, Ying Fan, Xiulan Peng, Xiaojun Gong, Liwei Shao

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Changjiang LeiDepartment of General Surgery, The Fifth Hospital of Wuhan Wuhan 430000, Hubei, China.
Ying FanDepartment of Cardiology, The Fifth Hospital of Wuhan Wuhan 430000, Hubei, China.
Xiulan PengDepartment of Oncology, The Fifth Hospital of Wuhan Wuhan 430000, Hubei, China.
Xiaojun GongDepartment of General Surgery, The Fifth Hospital of Wuhan Wuhan 430000, Hubei, China.
Liwei ShaoDepartment of General Surgery, The Fifth Hospital of Wuhan Wuhan 430000, Hubei, China.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B infection is a major global health problem and a primary cause of hepatocellular carcinoma (HCC). While various antiviral treatments have been explored, there is not yet a reliable method for preventing the progression of chronic hepatitis B infection into HCC. Hepatitis B virus X protein (HBx) plays a major role in viral replication, chronic inflammation and the pathogenicity of chronic liver disease. Modulation of purinergic receptors using their specific agonists has become a popular new strategy for modifying disease processes. In the present study, we investigated the involvement of the P2Y

Indexed as

HBxHepatitis B virus (HBV)hepatocellular carcinomaliver diseaseNF157P2Y11purinergic receptors

Identifiers

PMID31217852
PMCPMC6556625
OpenAlexW2989924992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.