Evidence map›Paper›PMID 31217834›Full record

ArticleProceedings of meetings on acoustics. Acoustical Society of America2017

Reconstruction of nonlinear ultrasound field of an annular therapeutic array from acoustic holograms of its individual elements.

Vera A Khokhlova, Petr Yuldashev, Pavel Rosnitskiy, Oleg Sapozhnikov, Erik Dumont, Martijn Hoogenboom, Martijn den Brok, Jurgen Fütterer, Gosse Adema

Abstract read
In one paragraph

Article in Proceedings of meetings on acoustics. Acoustical Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Spatiotemporal Deconvolution of Hydrophone Response for Linear and Nonlinear Beams-Part II: Experimental Validation.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  3. Article
  4. Correction for Hydrophone Spatial Averaging Artifacts for Circular Sources.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vera A KhokhlovaM.V. Lomonosov Moscow State University, Moscow, 119991, RUSSIAN FEDERATION.
Petr YuldashevM.V. Lomonosov Moscow State University, Moscow, 119991, RUSSIAN FEDERATION.
Pavel RosnitskiyM.V. Lomonosov Moscow State University, Moscow, 119991, RUSSIAN FEDERATION.
Oleg SapozhnikovM.V. Lomonosov Moscow State University, Moscow, 119991, RUSSIAN FEDERATION.
Erik DumontImage Guided Therapy, Pessac, FRANCE.
Martijn HoogenboomRadboud University Medical Center, Nijmegen, NETHERLANDS.
Martijn den BrokRadboud University Medical Center, Nijmegen, NETHERLANDS.
Jurgen FüttererRadboud University Medical Center, Nijmegen, NETHERLANDS.
Gosse AdemaRadboud University Medical Center, Nijmegen, NETHERLANDS.

Funding

Nonlinear Acoustics in Calibration/Metrology of High Intensity Focused UltrasoundR01EB007643 · NIBIB · UNIVERSITY OF WASHINGTON · PI KHOKHLOVA, VERA · 2008 to 2020
$6.9M
NIBIB NIH HHS R01 EB007643
6 · The paper itself

Abstract

Acoustic holography method has been shown to provide accurate reconstruction of 3D ultrasound fields generated by various medical transducers including multi-element arrays as well as to set a boundary condition for nonlinear field modeling at high pressure levels. Here an approach of measuring holograms of individual array elements for modeling of an entire array field is proposed and tested for a 3 MHz 16-element annular array (48 mm diameter and 35 mm radius of curvature). The array is a part of a high intensity focused ultrasound system with magnetic resonance guidance used for developing thermal and mechanical methods of tissue ablation in mouse tumors. The holograms measured separately for each array element were combined together to obtain a boundary condition for the array with all operating elements. Modeling results were compared to low-amplitude beam scans and good agreement was demonstrated. Then, nonlinear field simulations were performed at increasing power outputs based on the 3D Westervelt equation. It was shown that the transducer is capable to produce focal waveforms with 140 MPa shock amplitude at 110 W acoustic power and thus is well suited for evaluating shock-based ablation therapies in small animals.

Identifiers

PMID31217834
PMCPMC6583799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.