Evidence map›Paper›PMID 31217741›Full record

ArticleInternational journal of medical sciences2019

Protective Effects of Rosmarinic Acid against Selenite-Induced Cataract and Oxidative Damage in Rats.

Chia-Fang Tsai, Jia-Ying Wu, Yu-Wen Hsu

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The future of cataract surgery.Eye (London, England) · 2025
    Review
  8. Intermediate filaments and their associated molecules.Journal of biomedical research · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Identification of spontaneous age-related cataract inZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  13. Exploring the Traditional Uses ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  14. Effect ofNutrients · 2023
    Article
  15. Astragalin attenuates diabetic cataractsInternational journal of ophthalmology · 2023
    Article
  16. Article
  17. Antimicrobial Screening and Fungicidal Properties ofPlants (Basel, Switzerland) · 2022
    Article
  18. Review
  19. Exploring the Protective Effect and Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Chia-Fang TsaiDepartment of Applied Cosmetology, National Tainan Junior College of Nursing, Tainan, Taiwan.
Jia-Ying WuDepartment of Biotechnology, TransWorld University, Yunlin County, Taiwan.
Yu-Wen HsuDepartment of Optometry, Da-Yeh University, Changhua, Taiwan.
Dayeh University · TWNational Tainan Institute of Nursing · TWTransWorld University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cataracts are the major cause of blindness and are associated with oxidative damage of the lens. In the present study, the aim was to evaluate the protective effects of rosmarinic acid on selenite-induced cataractogenesis in Sprague-Dawley rat pups. The animals were randomly divided into five groups, each of which consisted of 10 rat pups. Group I served as normal control (vehicle administration). For testing cataract induction, animals of Groups II, III, IV, and V were administered a single subcutaneous injection of sodium selenite (2.46 mg/kg body weight) on postpartum day 12. After sodium selenite intoxication, Group II served as control selenite. From the 11th day through the 17th day, Groups III-V received rosmarinic acid intraperitoneally at doses of 5, 10, and 50 mg/kg, respectively. On postpartum day 24, the rat pups were examined for cataract formation, and the lenses were isolated for further analysis of proteins and oxidative damage indicators. Selenite caused significant (

Indexed as

AnimalsAntioxidantsCatalaseCataractCinnamatesDepsidesDisease Models, AnimalGene ExpressionHumansLipid PeroxidationOxidative StressPlant ExtractsRatsRosmarinic AcidSelenious AcidSuperoxide DismutaseAntioxidantsCatalaseCinnamatesDepsidesPlant ExtractsRosmarinic AcidSelenious AcidSuperoxide Dismutasecataractogenesisoxidative damagerosmarinic acidsodium selenite

Identifiers

PMID31217741
PMCPMC6566745
OpenAlexW2947506452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.