ArticleScientific reports2019
Neighbourhood socioeconomic deprivation and allostatic load: a multi-cohort study.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Posttraumatic Stress Disorder, Health-Related Social Needs, and Cognitive Outcomes in US Veterans.JAMA network open · 2026Article
- Neighborhood Deprivation and Voice and Reflux Symptom Burden in a Tertiary Laryngology Cohort.The Laryngoscope · 2026Article
- Associations between inflammation markers (CRP and IL-6) and depression among adolescents and young adults in Soweto and Durban, South Africa.Brain, behavior, & immunity - health · 2026Article
- Does time heal all wounds? Examining the lasting impact of historic redlining on contemporary racial disparities in allostatic load in Baltimore, Maryland.Ethnicity & health · 2026Article
- Relationship between socioeconomic inequality and multimorbidity progression in UK Biobank data.Communications medicine · 2026Article
- Impact of Social Vulnerability and Allostatic Load on Postoperative Outcomes.Annals of surgical oncology · 2026Article
- The unified cardiometabolic disease continuum: mechanistic stages of a single pathophysiological process.Frontiers in endocrinology · 2026Review
- Neighbourhood Socioeconomic Deprivation and Older Adults' Cognitive Decline in Porto, Portugal: A 13-Year (2005-2018) Longitudinal Analysis Using the Population-Based EPIPorto Cohort.International journal of public health · 2026Article
- Mediating pathways between area-level deprivation and hypertension in Nepal: the role of nutritional status, food insecurity, and health behaviors.BMC public health · 2025Article
- Associations of community socioeconomic factors and opioid use disorder across an urban-to-rural spectrum in Pennsylvania: an electronic health record-based case-control study.Social psychiatry and psychiatric epidemiology · 2025Article
- The Hidden Burden: Impact of Allostatic Load on Colorectal Cancer Surgery Outcomes.Annals of surgical oncology · 2025Article
- Cardiometabolic state links neurovascular burden with brain structure and function: Evidence from EEG and MRI.NeuroImage · 2025Article
- Allostatic load and cancer risk, progression, and mortality in epidemiologic studies.American journal of epidemiology · 2025Article
- Structural inequality and temporal brain dynamics across diverse samples.Clinical and translational medicine · 2024Article
- Association of Occupational and Leisure-Time Physical Activity With Allostatic Load.American journal of preventive medicine · 2024Article
- Connecting to Community: A Social Identity Approach to Neighborhood Mental Health.Personality and social psychology review : an official journal of the Society for Personality and Social Psychology, Inc · 2024Review
- Components of Residential Neighborhood Deprivation and Their Impact on the Likelihood of Live-Donor and Preemptive Kidney Transplantation.Clinical transplantation · 2024Article
- Community credit scores and community socioeconomic deprivation in association with type 2 diabetes across an urban to rural spectrum in Pennsylvania: a case-control study.BMJ public health · 2024Article
- Association Between Neighborhood Opportunity, Allostatic Load, and All-Cause Mortality in Patients With Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Article
- A synergetic turn in cognitive neuroscience of brain diseases.Trends in cognitive sciences · 2024Review
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Authors and funding
11 authors.
Funding
Abstract
Living in deprived neighbourhoods may have biological consequences, but few studies have assessed this empirically. We examined the association between neighbourhood deprivation and allostatic load, a biological marker of wear and tear, taking into account individual's socioeconomic position. We analysed data from three cohort studies (CoLaus-Switzerland; EPIPorto-Portugal; Whitehall II-UK) comprising 16,364 participants. We defined allostatic load using ten biomarkers of dysregulated metabolic, cardiovascular, and inflammatory systems (body mass index; waist circumference; total, high and low density lipoprotein cholesterol; triglycerides; glucose; systolic and diastolic blood pressure; C-reactive protein). Mixed Poisson regression models were fitted to examine associations with neighbourhood deprivation (in quintiles, Q1-least deprived as reference). After adjustment for confounding variables, participants living in the most deprived quintile had 1.13 times higher allostatic load than those living in the least deprived quintile (Relative Risk, RR, for Q2 RR = 1.06, 95% CI 1.03-1.09; Q3 = 1.06, 1.03-1.10; Q4 = 1.09, 1.06-1.12; Q5 = 1.13, 1.09-1.16). This association was partially modified by individual's socioeconomic position, such that the relative risk was higher in participants with low socioeconomic position (Q5 vs Q1 1.16, 1.11-1.22) than those with high socioeconomic position (Q5 vs Q1 1.07, 1.01-1.13). Neighbourhood deprivation is associated with biological wear and tear, suggesting that neighbourhood-level interventions may yield health gains.
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