Evidence map›Paper›PMID 31217309›Full record

ArticlePediatrics2019

Prevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in Children.

Cristin Q Fritz, Kathryn M Edwards, Wesley H Self, Carlos G Grijalva, Yuwei Zhu, Sandra R Arnold, Jonathan A McCullers, Krow Ampofo, Andrew T Pavia, Richard G Wunderink and 4 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Health state utilities associated with invasive pneumococcal disease, pneumonia, and recurrent acute otitis media in young children.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Adenovirus andFrontiers in pediatrics · 2024
    Article
  12. Management of Pediatric Pneumonia: A Decade After the Pediatric Infectious Diseases Society and Infectious Diseases Society of America Guideline.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  13. Review
  14. Article
  15. NeonatalFrontiers in microbiology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Challenges of Antibiotic Stewardship in the Pediatric and Neonatal Intensive Care Units.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Cristin Q FritzMonroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee; cristin.fritz@childrenscolorado.org.
Kathryn M EdwardsMonroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.
Wesley H SelfSchool of Medicine, Vanderbilt University, Nashville, Tennessee.
Carlos G GrijalvaSchool of Medicine, Vanderbilt University, Nashville, Tennessee.
Yuwei ZhuSchool of Medicine, Vanderbilt University, Nashville, Tennessee.
Sandra R ArnoldLe Bonheur Children's Hospital, Memphis, Tennessee.
Jonathan A McCullersLe Bonheur Children's Hospital, Memphis, Tennessee.
Krow AmpofoUniversity of Utah Health Sciences Center, Salt Lake City, Utah.
Andrew T PaviaUniversity of Utah Health Sciences Center, Salt Lake City, Utah.
Richard G WunderinkFeinberg School of Medicine, Northwestern University, Chicago, Illinois.
Evan J AndersonSchool of Medicine, Emory University, Atlanta, Georgia; and.
Anna M BramleyCenters for Disease Control and Prevention, Atlanta, Georgia.
Seema JainCenters for Disease Control and Prevention, Atlanta, Georgia.
Derek J WilliamsMonroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee.
Vanderbilt University · USCenters for Disease Control and Prevention · USUniversity of Utah · USEmory University · USLe Bonheur Children's Hospital · USMonroe Carell Jr. Children's Hospital · USNorthwestern University · USUniversity of Tennessee Health Science Center · USVanderbilt Health · US

Funding

Development and Validation of a Clinical Prediction Rule for Pediatric PneumoniaK23AI104779 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILLIAMS, DEREK J. · 2013 to 2016
$688k
NIAID NIH HHS K23 AI104779
6 · The paper itself

Abstract

backgroundPrevious studies examining bacteremia in hospitalized children with pneumonia are limited by incomplete culture data. We sought to determine characteristics of children with bacteremic pneumonia using data from a large prospective study with systematic blood culturing.

methodsChildren <18 years hospitalized with pneumonia and enrolled in the multicenter Etiology of Pneumonia in the Community study between January 2010 and June 2012 were eligible. Bivariate comparisons were used to identify factors associated with bacteremia. Associations between bacteremia and clinical outcomes were assessed by using Cox proportional hazards regression for length of stay and logistic regression for ICU admission and invasive mechanical ventilation or shock.

resultsBlood cultures were obtained in 2143 (91%) of 2358 children; 46 (2.2%) had bacteremia. The most common pathogens were

conclusionsBacteremia was uncommonly detected in this large multicenter cohort of children hospitalized with community-acquired pneumonia but was associated with severe disease.

Indexed as

AdolescentAnti-Bacterial AgentsBacteremiaBlood CultureChildChild, PreschoolCommunity-Acquired InfectionsCritical CareFemaleHumansInfantLength of StayMalePneumonia, BacterialPrevalenceProportional Hazards ModelsAnti-Bacterial Agents

Identifiers

PMID31217309
PMCPMC6615516
OpenAlexW2949073548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.