Evidence map›Paper›PMID 31217244›Full record

ArticleJournal of virology2019

ANP32 Proteins Are Essential for Influenza Virus Replication in Human Cells.

Ecco Staller, Carol M Sheppard, Peter J Neasham, Bhakti Mistry, Thomas P Peacock, Daniel H Goldhill, Jason S Long, Wendy S Barclay

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 101 citations in OpenAlex.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ecco StallerSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0002-8443-5559
Carol M SheppardSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0002-3285-3804
Peter J NeashamSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.
Bhakti MistrySection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0001-5455-0479
Thomas P PeacockSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0001-7077-2928
Daniel H GoldhillSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0003-4597-5963
Jason S LongSection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom.ORCID 0000-0002-0251-6487
Wendy S BarclaySection of Molecular Virology, Imperial College London, St Mary's Campus, London, United Kingdom w.barclay@imperial.ac.uk.ORCID 0000-0002-3948-0895
Imperial College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K002465/1Biotechnology and Biological Sciences Research Council BB/L015129/1Biotechnology and Biological Sciences Research Council BB/R013071/1Wellcome Trust 104931/Z/14/ZWellcome Trust 205100
6 · The paper itself

Abstract

ANP32 proteins have been implicated in supporting influenza virus replication, but most of the work to date has focused on the ability of avian Anp32 proteins to overcome restriction of avian influenza polymerases in human cells. Using a CRISPR approach, we show that the human

Indexed as

AnimalsBetainfluenzavirusCell Cycle ProteinsCell LineCRISPR-Cas SystemsDisease Models, AnimalHumansInfluenza A virusMiceNerve Tissue ProteinsNuclear ProteinsPoint MutationProtein DomainsRNA-Binding ProteinsRNA-Dependent RNA PolymeraseViral ProteinsANP32A protein, humanAnp32a protein, mouseANP32B protein, humanAnp32b protein, mouseCell Cycle ProteinsNerve Tissue ProteinsNuclear ProteinsRNA-Binding ProteinsRNA-Dependent RNA PolymeraseViral ProteinsANP32ANP32AANP32BCRISPRhost factorinfluenzapolymerasereplicationvirus

Identifiers

PMID31217244
PMCPMC6694824
OpenAlexW2953156505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.