Evidence map›Paper›PMID 31217003›Full record

ArticleBMC infectious diseases2019

Tuberculosis treatment in the private healthcare sector in India: an analysis of recent trends and volumes using drug sales data.

Nimalan Arinaminpathy, Deepak Batra, Nilesh Maheshwari, Kishan Swaroop, Lokesh Sharma, Kuldeep Singh Sachdeva, Sunil Khaparde, Raghuram Rao, Devesh Gupta, Bhavin Vadera and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  19. Accelerating progress towards ending tuberculosis in India.The Indian journal of medical research · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Nimalan ArinaminpathyDepartment of Infectious Disease Epidemiology, Imperial College School of Medicine, London, UK. nim.pathy@imperial.ac.uk.ORCID http://orcid.org/0000-0002-0412-150X
Deepak BatraIQVIA, New Delhi, India.
Nilesh MaheshwariIQVIA, New Delhi, India.
Kishan SwaroopIQVIA, New Delhi, India.
Lokesh SharmaIQVIA, New Delhi, India.
Kuldeep Singh SachdevaCentral TB Division, New Delhi, India.
Sunil KhapardeMinistry of Health and Family Welfare, Mumbai, India.
Raghuram RaoCentral TB Division, New Delhi, India.
Devesh GuptaCentral TB Division, New Delhi, India.
Bhavin VaderaCentral TB Division, New Delhi, India.
Sreenivas A NairStop TB Partnership, Geneva, Switzerland.
Kiran RadeWHO India country office, New Delhi, India.
Sameer KumtaBill and Melinda Gates Foundation, New Delhi, India.
Puneet DewanIndependent consultant, Seattle, USA.
IQVIA (India) · INNew Delhi Tuberculosis Center · INGates Foundation · USIndependent Sector · USMinistry of Health and Family Welfare · INNIHR Imperial Biomedical Research Centre · GBWorld Health Organization - India · IN

Funding

Bill and Melinda Gates Foundation OPP1095710Medical Research Council MR/R015600/1World Health Organization 001
6 · The paper itself

Abstract

backgroundThere is a pressing need for systematic approaches for monitoring how much TB treatment is ongoing in the private sector in India: both to cast light on the true scale of the problem, and to help monitor the progress of interventions currently being planned to address this problem.

methodsWe used commercially available data on the sales of rifampicin-containing drugs in the private sector, adjusted for data coverage and indication of use. We examined temporal, statewise trends in volumes (patient-months) of TB treatment from 2013 to 2016. We additionally analysed the proportion of drugs that were sold in combination packaging (designed to simplify TB treatment), or as loose pills.

resultsDrug sales suggest a steady trend of TB treatment dispensed by the private sector, from 18.4 million patient-months (95% CI 17.3-20.5) in 2013 to 16.8 patient-months (95% CI 15.5-19.0) in 2016. Overall, seven of 29 states in India accounted for more than 70% of national-level TB treatment volumes, including Uttar Pradesh, Maharashtra and Bihar. The overwhelming majority of TB treatment was dispensed not as loose pills, but in combination packaging with other TB drugs, accounting for over 96% of private sector TB treatment in 2017.

conclusionsOur findings suggest consistent levels of TB treatment in the private sector over the past 4 years, while highlighting specific states that should be prioritized for intervention. Drug sales data can be helpful for monitoring a system as large, disorganised and opaque as India's private sector.

Indexed as

Antibiotics, AntitubercularHealth Care SectorHumansIndiaRifampinTuberculosisAntibiotics, AntitubercularRifampinIndiaPrivate sectorTuberculosis

Identifiers

PMID31217003
PMCPMC6584981
OpenAlexW2950490819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.