ArticleEpigenetics2019
Associations between placental CpG methylation of metastable epialleles and childhood body mass index across ages one, two and ten in the Extremely Low Gestational Age Newborns (ELGAN) cohort.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program.Environmental health perspectives · 2024Trial
- Epigenetics and childhood obesity: DNA methylation coordinates environment and gene regulation.Endocrine reviews · 2026Review
- Two Sides of a Coin: Molecular, metabolic, and Phenotypic Convergence in Pediatric Undernutrition and Obesity.Current obesity reports · 2026Review
- Epigenetic mechanisms linking the perinatal environment, the placenta, and maternal and child health outcomes: evidence for sexual dimorphism.Environmental epigenetics · 2026Article
- Transcriptomic profiling of DYT-TOR1A patient-derived iPSC reveals dysregulation in extracellular matrix, lipid metabolism, and Chr22q11.23.BMC medical genomics · 2025Article
- Analysis of prenatal medication use and placental epigenetic gestational age in extremely low gestational age newborns (ELGANs) highlight relationships to aspirin use during pregnancy.Clinical epigenetics · 2025Article
- Placental DNA methylation key topics: sex- and cell-type specificity, mediation, multi-omics, and biomarker discovery.Epigenomics · 2025Review
- Genetic associations between orexin genes and phenotypes related to behavioral regulation in humans, including substance use.Molecular psychiatry · 2025Article
- Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids.Pediatric research · 2024Article
- Differentially methylated regions interrogated for metastable epialleles associate with offspring adiposity.Epigenomics · 2024Article
- Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns.BMC biology · 2023Article
- A multi-omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm.Autism research : official journal of the International Society for Autism Research · 2023Article
- Comparison of methanol fixation versus cryopreservation of the placenta for metabolomics analysis.Scientific reports · 2023Article
- CpG methylation patterns in placenta and neonatal blood are differentially associated with neonatal inflammation.Pediatric research · 2023Article
- Differential placental CpG methylation is associated with chronic lung disease of prematurity.Pediatric research · 2022Article
- Placental genomics mediates genetic associations with complex health traits and disease.Nature communications · 2022Article
- Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research.Frontiers in toxicology · 2022Article
- Comparing the Predictivity of Human Placental Gene, microRNA, and CpG Methylation Signatures in Relation to Perinatal Outcomes.Toxicological sciences : an official journal of the Society of Toxicology · 2021Article
- CUE: CpG impUtation ensemble for DNA methylation levels across the human methylation450 (HM450) and EPIC (HM850) BeadChip platforms.Epigenetics · 2021Article
- Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm.Molecular autism · 2020Article
Corrections and comments
- Erratum issuedCorrection.2021
Authors and funding
7 authors at 2 institutions in 1 country.
Jeliyah ClarkDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.
Elizabeth MartinEpigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park , NC , USA.
Catherine M BulkaDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.
Lisa SmeesterDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.
Hudson P SantosInstitute for Environmental Health Solutions, Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.ORCID 0000-0002-4040-366X
T Michael O'SheaDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of North Carolina , Chapel Hill , NC , USA.ORCID 0000-0001-6692-911X
Rebecca C FryDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina , Chapel Hill , NC , USA.
University of North Carolina at Chapel Hill · USNational Institute of Environmental Health Sciences · US
Funding
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3MBiostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3MThe Role of the Placenta-Brain Axis in Children's NeurodevelopmentUH3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Rebecca Fry, Michael O'SHEA · 2018 to 2026
$21.9MTOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0MEnvironment, Epigenetics, Neurodevelopment & Health of Extremely Preterm ChildrenUG3OD023348 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA, O'SHEA, MICHAEL · 2016 to 2024
$7.4MPlacental Epigenome and Brain Dysfunction after Preterm BirthR01HD092374 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA, O'SHEA, MICHAEL · 2017 to 2021
$3.2MPlacental DNA Methylation, Maternal Hardship and Child Neurodevelopmental OutcomesK23NR017898 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SANTOS, HUDSON · 2018 to 2020
$395kNICHD NIH HHS R01 HD092374NIEHS NIH HHS P30 ES010126NIEHS NIH HHS T32 ES007018NIEHS NIH HHS T32 ES007126NIH HHS UG3 OD023348NIH HHS UH3 OD023348NINR NIH HHS K23 NR017898
Abstract
The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that
Indexed as
Body Mass IndexDNA MethylationEpigenesis, GeneticAdultAllelesCpG IslandsFemaleGenetic LociHumansInfant, NewbornInfant, Very Low Birth WeightMalePlacentaPregnancybody mass indexchild healthCpG methylationepigeneticsMetastable epiallelesplacenta
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.