Evidence map›Paper›PMID 31216927›Full record

ArticleEpigenetics2019

The histone lysine demethylase

Vitor Braga Rissi, Werner Giehl Glanzner, Mariana Priotto De Macedo, Karina Gutierrez, Hernan Baldassarre, Paulo Bayard Dias Gonçalves, Vilceu Bordignon

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Chromatin role in early programming of embryos.Animal frontiers : the review magazine of animal agriculture · 2021
    Article
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  9. Article
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  12. LncRNACell transplantation
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vitor Braga RissiLaboratory of Biotechnology and Animal Reproduction - BioRep, Federal University of Santa Maria (UFSM) , Santa Maria , RS , Brazil.ORCID 0000-0001-9412-7931
Werner Giehl GlanznerDepartment of Animal Science, McGill University , Sainte Anne de Bellevue , QC , Canada.ORCID 0000-0001-6467-8687
Mariana Priotto De MacedoDepartment of Animal Science, McGill University , Sainte Anne de Bellevue , QC , Canada.ORCID 0000-0001-7878-0535
Karina GutierrezDepartment of Animal Science, McGill University , Sainte Anne de Bellevue , QC , Canada.
Hernan BaldassarreDepartment of Animal Science, McGill University , Sainte Anne de Bellevue , QC , Canada.
Paulo Bayard Dias GonçalvesLaboratory of Biotechnology and Animal Reproduction - BioRep, Federal University of Santa Maria (UFSM) , Santa Maria , RS , Brazil.
Vilceu BordignonDepartment of Animal Science, McGill University , Sainte Anne de Bellevue , QC , Canada.ORCID 0000-0001-7076-7707
McGill University · CAUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing evidence that histone lysine demethylases (KDMs) play critical roles in the regulation of embryo development. This study investigated if KDM7A, a lysine demethylase known to act on mono-(me1) and di-(me2) methylation of H3K9 and H3K27, participates in the regulation of early embryo development. Knockdown of

Indexed as

Cell LineageAnimalsBlastocystCells, CulturedFemaleGene Expression Regulation, DevelopmentalHistone CodeHistone DemethylasesSwineHistone Demethylasescell differentiationembryo developmenthistone methylationLysine demethylasesporcine

Identifiers

PMID31216927
PMCPMC6773414
OpenAlexW2950784840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.