Evidence map›Paper›PMID 31216696›Full record

ReviewInternational journal of molecular sciences2019

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches.

Peter Valent, Cem Akin, Karoline V Gleixner, Wolfgang R Sperr, Andreas Reiter, Michel Arock, Massimo Triggiani

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
  2. Hereditary alpha tryptasemia and clinical implications.World journal of clinical cases · 2025
    Review
  3. Review
  4. Epidemiology of mastocytosis: a population-based study (Sweden).Acta oncologica (Stockholm, Sweden) · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. How to evaluate the patient with a suspected mast cell disorder and how/when to manage symptoms.Hematology. American Society of Hematology. Education Program · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Peter ValentDepartment of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria. peter.valent@meduniwien.ac.at.ORCID 0000-0003-0456-5095
Cem AkinDivision of Allergy and Clinical Immunology, University of Michigan, Ann Arbor, MI 48106, USA. cemakin@umich.edu.
Karoline V GleixnerDepartment of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria. karoline.gleixner@meduniwien.ac.at.
Wolfgang R SperrDepartment of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria. wolfgang.r.sperr@meduniwien.ac.at.
Andreas ReiterIII. Medizinische Klinik, Universitätsmedizin Mannheim, 68167 Mannheim, Germany. andreas.reiter@uum.de.
Michel ArockDepartment of Hematological Biology, Pitié-Salpêtrière Hospital, Pierre et Marie Curie University (UPMC), 75005 Paris, France. arock@ens-cachan.fr.
Massimo TriggianiDivision of Allergy and Clinical Immunology, University of Salerno, 84131 Salerno, Italy. mtriggiani@unisa.it.
Medical University of Vienna · ATHeidelberg University · DESorbonne Université · FRUniversity of Michigan · USUniversity of Salerno · IT

Funding

Austrian Science Fund F4701-B20Austrian Science Fund F4704-B20
6 · The paper itself

Abstract

Mastocytosis is a hematopoietic neoplasm defined by abnormal expansion and focal accumulation of clonal tissue mast cells in various organ-systems. The disease exhibits a complex pathology and an equally complex clinical behavior. The classification of the World Health Organization (WHO) divides mastocytosis into cutaneous forms, systemic variants, and localized mast cell tumors. In >80% of patients with systemic mastocytosis (SM), a somatic point mutation in

Indexed as

Precision MedicineAnaphylaxisBiomarkersBone DiseasesBone MarrowDisease ManagementHumansImmunoglobulin EMast CellsMastocytosisMastocytosis, SystemicMutationPrognosisProto-Oncogene Proteins c-kitRiskSeverity of Illness IndexBiomarkersImmunoglobulin EKIT protein, humanProto-Oncogene Proteins c-kitallergyIgEKIT D816Vmast cellsMCASpersonalized medicinetryptase

Identifiers

PMID31216696
PMCPMC6627900
OpenAlexW2951419909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.