ArticlePLoS biology2019
Neutrality in the Metaorganism.
Article in PLoS biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
64 citing papers in PubMed.
- Rare Taxa and Stochastic Drift Drive the Microbiome Assembly of the Invasive Pest Drosophila suzukii, While Host Filtering Structures the Grape Sour Rot Community.Microbial ecology · 2026Article
- The island biology of the host microbiome.Trends in microbiology · 2026Review
- Insights from healthy mares reveal that mammalian uteri harbor a diverse virome.Scientific reports · 2026Article
- Host-Associated Bacterial Community Changes After Laboratory Introduction Vary With Wolbachia Presence.Environmental microbiology · 2026Article
- Horizontal Dispersal Limitation and Vertical Environmental Filtering Drive Ciliate Community Assembly in a Tibetan Plateau Deep Lake.Microorganisms · 2026Article
- Community assembly modeling of the microbiome within Barrett's esophagus and esophageal adenocarcinoma.BMC genomics · 2026Article
- Linking complex microbial interactions and dysbiosis through a disordered Lotka-Volterra model.eLife · 2026Article
- Cooperation destabilizes communities, but competition pays the price.Journal of biosciences · 2026Article
- A two-hit ecological framework linking social context to caries-associated microbiome shifts in children.Journal of oral microbiology · 2026Article
- Within-host microbial selection and multiple microbial generations buffer the loss of host fitness under environmental change.FEMS microbiology ecology · 2025Article
- Gut metagenomes reveal interactions between dietary restriction, ageing and the microbiome in genetically diverse mice.Nature microbiology · 2025Article
- Deterministic and stochastic effects drive the gut microbial diversity in cucurbit-feeding fruit flies (Diptera, Tephritidae).PloS one · 2025Article
- Influence of Temperature and Saline Conditions on Bacteria Naturally Associated With the Cnidarian HostInternational journal of microbiology · 2025Article
- Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems.Current clinical microbiology reports · 2025Review
- Environmental microbial reservoir influences the bacterial communities associated with Hydra oligactis.Scientific reports · 2024Article
- Stochastic models allow improved inference of microbiome interactions from time series data.PLoS biology · 2024Article
- Habitat specificity modulates the bacterial biogeographic patterns in the Southern Ocean.FEMS microbiology ecology · 2024Article
- Emergent ecological patterns and modelling of gut microbiomes in health and in disease.PLoS computational biology · 2024Article
- Host specialization and spatial divergence of bacteria associated with Peltigera lichens promote landscape gamma diversity.Environmental microbiome · 2024Article
- Insect-microbe interactions and their influence on organisms and ecosystems.Ecology and evolution · 2024Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Almost all animals and plants are inhabited by diverse communities of microorganisms, the microbiota, thereby forming an integrated entity, the metaorganism. Natural selection should favor hosts that shape the community composition of these microbes to promote a beneficial host-microbe symbiosis. Indeed, animal hosts often pose selective environments, which only a subset of the environmentally available microbes are able to colonize. How these microbes assemble after colonization to form the complex microbiota is less clear. Neutral models are based on the assumption that the alternatives in microbiota community composition are selectively equivalent and thus entirely shaped by random population dynamics and dispersal. Here, we use the neutral model as a null hypothesis to assess microbiata composition in host organisms, which does not rely on invoking any adaptive processes underlying microbial community assembly. We show that the overall microbiota community structure from a wide range of host organisms, in particular including previously understudied invertebrates, is in many cases consistent with neutral expectations. Our approach allows to identify individual microbes that are deviating from the neutral expectation and are therefore interesting candidates for further study. Moreover, using simulated communities, we demonstrate that transient community states may play a role in the deviations from the neutral expectation. Our findings highlight that the consideration of neutral processes and temporal changes in community composition are critical for an in-depth understanding of microbiota-host interactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.