Evidence map›Paper›PMID 31216191›Full record

ArticleAmerican journal of physiology. Cell physiology2019

Wide field of view quantitative imaging of cellular ATP release.

Ju Jing Tan, Olga Ponomarchuk, Ryszard Grygorczyk, Francis Boudreault

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ju Jing TanCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Olga PonomarchukCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Ryszard GrygorczykCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.ORCID 0000-0002-9798-7651
Francis BoudreaultCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Centre Hospitalier de l’Université de Montréal · CA

Funding

CIHR MOP64364
6 · The paper itself

Abstract

Although several mechanical stressors promote ATP secretion from eukaryotic cells, few mechanosensitive pathways for ATP release have been precisely characterized and none have been clearly identified. To facilitate progress, we report here a wide field of view (∼20 × 20 mm sample area) imaging technique paired with a quantitative image analysis to accurately map the dynamics of ATP release from a cell population. The approach has been tested on A549 cells stretched at high initial strain rate (2-5 s

Indexed as

Stress, MechanicalA549 CellsAdenosine TriphosphateCell MembraneHumansMicroscopy, ElectronMolecular ImagingOsmotic PressureAdenosine TriphosphateATP releasebioluminescenceimagingmechanical stress

Identifiers

PMID31216191
PMCPMC6766621
OpenAlexW2949676553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.