ArticleJMIR mHealth and uHealth2019
A Medication Adherence App for Children With Sickle Cell Disease: Qualitative Study.
Article in JMIR mHealth and uHealth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Potential associations between behavior change techniques and engagement with mobile health apps: a systematic review.Frontiers in psychology · 2023Pooled it
- Supporting Medication Adherence in Parkinson's Through Education: A Scoping Review of Interventions.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Health equity in sickle cell disease: overcoming barriers to care in marginalized communities.Annals of medicine and surgery (2012) · 2025Review
- Differences in HRQOL among Children with SCD Who Received Hydroxyurea and Those Who Did Not: A Quantitative Comparison Study.Oman medical journal · 2025Article
- Transition Readiness of Pediatric Sickle Cell Patients to Adult Clinic in a Teaching Hospital, Ghana.Advances in hematology · 2025Article
- A meta-ethnography of how children and young people with chronic non-cancer pain and their families experience and understand their condition, pain services, and treatments.The Cochrane database of systematic reviews · 2023Review
- Barriers to medication adherence in sickle cell disease: A comprehensive theory-based evaluation using the COM-B model.Pediatric blood & cancer · 2023Article
- Effectiveness of daily educational message on pregnancy anemia prevention behavior and knowledge: A pilot randomized controlled trial.Journal of education and health promotion · 2023Article
- Development of an individualized WeChat mini program-based intervention to increase adherence to dietary recommendations applying the behaviour change wheel among individuals with metabolic syndrome.Annals of medicine · 2023Article
- Individuals with Sickle Cell Disease Using SBAR as a Communication Tool: A Pilot Study.International journal of environmental research and public health · 2022Article
- Barriers to hydroxyurea use from the perspectives of providers, individuals with sickle cell disease, and families: Report from a U.S. regional collaborative.Frontiers in genetics · 2022Article
- Toward a Behavior Theory-Informed and User-Centered Mobile App for Parents to Prevent Infant Falls: Development and Usability Study.JMIR pediatrics and parenting · 2021Article
- Real-life isoniazid and rifampicin plasma concentrations in children: a tool for therapeutic drug monitoring of tuberculosis.BMC infectious diseases · 2021Article
- Opportunities for Mobile App-Based Adherence Support for Children With Tuberculosis in South Africa.JMIR mHealth and uHealth · 2020Article
- Adherence to Medication During Transition to Adult Services.Paediatric drugs · 2020Review
- Development of the InCharge Health Mobile App to Improve Adherence to Hydroxyurea in Patients With Sickle Cell Disease: User-Centered Design Approach.JMIR mHealth and uHealth · 2020Article
- Safety concerns with consumer-facing mobile health applications and their consequences: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundYoung people with sickle cell disease (SCD) often demonstrate low medication adherence and low motivation for effectively self-managing their condition. The growing sophistication of mobile phones and their popularity among young people render them a promising platform for increasing medication adherence. However, so far, few apps targeting SCD have been developed from research with the target population and underpinned with theory and evidence.
objectiveThe aim of this study was to develop a theory-and-evidence-based medication adherence app to support children and adolescents with SCD.
methodsThe Behavior Change Wheel (BCW), a theoretically based intervention development framework, along with a review of the literature, 10 interviews with children and adolescents with SCD aged between 12 and 18 years, and consultation with experts informed app development. Thematic analysis of interviews provided relevant theoretical and evidence-based components to underpin the design and development of the app.
resultsFindings suggested that some patients had lapses in memory for taking their medication (capability); variation in beliefs toward the effectiveness of medication and confidence in self-managing their condition (motivation); a limited time to take medication; and barriers and enablers within the changing context of social support during the transition into adulthood (opportunity). Steps were taken to select the appropriate behavioral change components (involving behavior change techniques [BCTs] such as information on antecedents, prompts/cues; self-monitoring of the behavior; and social support) and translate them into app features designed to overcome these barriers to medication adherence.
conclusionsPatients with SCD have complex barriers to medication adherence necessitating the need for comprehensive models of behavior change to analyze the problem. Children and adolescents require an app that goes beyond simple medication reminders and takes into account the patient's beliefs, emotions, and environmental barriers to medication adherence.
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