Evidence map›Paper›PMID 31215447›Full record

ArticleReproductive health2019

Perceptions of pregnancy occurring among HIV-serodiscordant couples in Kenya.

Grace Kimemia, Kenneth Ngure, Jared M Baeten, Connie Celum, Kristin Dew, Njambi Njuguna, Nelly Mugo, Renee Heffron

Open access · goldAbstract read
In one paragraph

Article in Reproductive health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. "AIDS care · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Integration of family planning services into health care for HIV-positive women in Botswana.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Living with Discordance: A Qualitative Description of the Challenges Faced by HIV Negative Married Women.International journal of community based nursing and midwifery · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Grace KimemiaAfrican Population & Health Research Center, Nairobi, Kenya.
Kenneth NgureDepartment of Community Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Jared M BaetenDepartment of Global Health, University of Washington, 325 Ninth Avenue Box 359927, Seattle, WA, 98104, USA.
Connie CelumDepartment of Global Health, University of Washington, 325 Ninth Avenue Box 359927, Seattle, WA, 98104, USA.
Kristin DewDepartment of Human Centered Design and Engineering, University of Washington, Seattle, USA.
Njambi NjugunaFHI360, Nairobi, Kenya.
Nelly MugoCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Renee HeffronDepartment of Global Health, University of Washington, 325 Ninth Avenue Box 359927, Seattle, WA, 98104, USA. rheffron@uw.edu.ORCID http://orcid.org/0000-0001-6039-0352
University of Washington · USAfrican Population and Health Research Center · KEJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Antiretroviral periconception HIV prevention for HIV discordant couplesR00HD076679 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2015 to 2017
$742k
Enhancing safer conception for HIV serodiscordant couples through mobile technologiesR21TW009908 · FIC · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2014 to 2015
$349k
Antiretroviral periconception HIV prevention for HIV discordant couplesK99HD076679 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2013 to 2014
$208k
FIC NIH HHS R21 TW009908FIC NIH HHS R21TW009908NIAID NIH HHS P30 AI027757NICHD NIH HHS K99 HD076679NICHD NIH HHS R00 HD076679NIMH NIH HHS R01 MH095507NIMH NIH HHS R01MH095507
6 · The paper itself

Abstract

backgroundAmong HIV serodiscordant couples, most conception involves condomless sex and may confer a period with increased HIV transmission risk if HIV viral load is not suppressed and other precautions are not used. Safer conception strategies enable HIV serodiscordant couples to attain their pregnancy goals while markedly reducing this risk. We explored the perceptions and beliefs held by HIV serodiscordant couples and health care providers concerning pregnancy among HIV serodiscordant couples in Kenya and gathered their thoughts about how these might influence use of safer conception methods.

methodsWe conducted 20 Key Informant Interviews (KIIs) with health care providers offering safer conception counseling and 21 In-Depth Interviews (IDIs) and 4 Focus Group Discussions (FGDs) with members of HIV serodiscordant couples with immediate pregnancy goals in Thika, Kenya. Data were analyzed using an inductive approach that identified two emergent themes: perceptions towards pregnancy among HIV serodiscordant couples and access to safer conception services.

resultsThe perceptions held by the community towards couples in HIV serodiscordant relationships having children were largely negative. The participants were aware of the increased HIV transmission risk to the HIV uninfected partners while trying to become pregnant. In the community, having biological children was cherished yet the majority of the couples shied away from accessing safer conception services offered at health facilities due to stigma and lack of knowledge of the existence of such services. Some providers had limited knowledge on safer conception strategies and services and consequently discouraged HIV serodiscordant couples from natural conception.

conclusionsNegative perceptions towards HIV serodiscordant couples becoming pregnant has hindered access to safer conception services. Therefore, there is need to create a supportive environment for HIV serodiscordant couples with fertility intentions that normalizes their desire to have children and informs the community about the availability of safer conception services.

Indexed as

AdultCounselingFemaleFertilizationHealth Knowledge, Attitudes, PracticeHealth PersonnelHIVHIV InfectionsHIV SeropositivityHumansInfectious Disease Transmission, VerticalKenyaMalePerceptionPregnancyPregnancy Complications, InfectiousHIV preventionperceptionsPregnancysafer conception

Identifiers

PMID31215447
PMCPMC6582525
OpenAlexW2950344943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.