Evidence map›Paper›PMID 31215275›Full record

ArticleLeukemia & lymphoma2019

The association between HLA and non-Hodgkin lymphoma subtypes, among a transplant-indicated population.

Charlie Zhong, Loren Gragert, Martin Maiers, Brian T Hill, Jean Garcia-Gomez, Ketevan Gendzekhadze, David Senitzer, Joo Song, Dennis Weisenburger, Leanne Goldstein and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia & lymphoma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Charlie ZhongDepartment of Computational and Quantitative Medicine, Beckman Research Institute, City of Hope, Duarte, CA, USA.ORCID 0000-0001-6973-887X
Loren GragertDepartment of Pathology and Laboratory Medicine, Tulane Cancer Center, Tulane University School of Medicine, New Orleans, LA, USA.
Martin MaiersBioinformatics Research, National Marrow Donor Program/Be The Match, Minneapolis, MN, USA.
Brian T HillHematologic Oncology and Blood Disorders, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Jean Garcia-GomezHistocompatibility Laboratory, City of Hope, Duarte, CA, USA.
Ketevan GendzekhadzeHistocompatibility Laboratory, City of Hope, Duarte, CA, USA.
David SenitzerHistocompatibility Laboratory, City of Hope, Duarte, CA, USA.
Joo SongDepartment of Pathology, City of Hope, Duarte, CA, USA.ORCID 0000-0003-3497-2513
Dennis WeisenburgerDepartment of Pathology, City of Hope, Duarte, CA, USA.
Leanne GoldsteinDivision of Biostatistics, Beckman Research Institute of the City of Hope, Duarte, CA, USA.ORCID 0000-0002-7721-6358
Sophia S WangDepartment of Computational and Quantitative Medicine, Beckman Research Institute, City of Hope, Duarte, CA, USA.
City of Hope · USCleveland Clinic · USNational Marrow Donor Program · USTulane University · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

Several studies have implicated HLA in non-Hodgkin lymphoma (NHL) subtype etiology. However, NHL patients indicated for stem cell transplants are underrepresented in these reports. We therefore evaluated the association between HLA and NHL subtypes among a transplant-indicated population. One thousand three hundred and sixty-six NHL patients HLA-typed and indicated for transplant at the City of Hope National Medical Center (Duarte, CA) were compared to 10,271 prospective donors. Odds ratios and 95% confidence intervals were calculated for HLA haplotype and alleles, adjusted for sex and age. The

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseAdultClinical Decision-MakingDiagnosis, DifferentialDisease ManagementFemaleHaplotypesHematopoietic Stem Cell TransplantationHLA AntigensHumansLeupeptinsLymphoma, Non-HodgkinMaleMiddle Agedacetylleucyl-leucyl-norleucinalHLA AntigensLeupeptinsbone marrow transplantEpidemiologyHLAlymphoma

Identifiers

PMID31215275
PMCPMC6858537
OpenAlexW2953197612

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.