ArticleCPT: pharmacometrics & systems pharmacology2019
Development of a Parsimonious Design for Optimal Classification of Exclusive Breastfeeding.
Article in CPT: pharmacometrics & systems pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04564222 (Double-Blind Cluster Randomized Controlled Trial of Chicken Liver and Eggshell Crackers in Mothers During Pregnancy and Lactation in a Disadvantaged Setting in Indonesia), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Double-Blind Cluster Randomized Controlled Trial of Chicken Liver and Eggshell Crackers in Mothers During Pregnancy and Lactation in a Disadvantaged Setting in Indonesia
Who cites it
6 citing papers in PubMed.
- Chicken liver and eggshell crackers are a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: a double-blind, cluster randomized controlled trial (SISTIK Growth Study).BMC pregnancy and childbirth · 2025Trial
- Human milk and total milk intakes of mixed fed infants: a cross-sectional study of infants aged 7-10 months.European journal of nutrition · 2026Article
- Maternal Perception vs Actual Breast Milk Supply: Protocol for an Observational Cross-Sectional Study.JMIR research protocols · 2026Observational
- Frequent Use of Baby Food Pouches in Infants and Young Children and Associations with Energy Intake and BMI: An Observational Study.Nutrients · 2024Observational
- Nutritional Implications of Baby-Led Weaning and Baby Food Pouches as Novel Methods of Infant Feeding: Protocol for an Observational Study.JMIR research protocols · 2021Article
- Examination of Carbohydrate Products in Feces Reveals Potential Biomarkers Distinguishing Exclusive and Nonexclusive Breastfeeding Practices in Infants.The Journal of nutrition · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A deuterium oxide dose-to-mother (DTM) technique is used to determine if an infant is exclusive breastfeeding (EBF). However, the DTM method is intensive, requiring seven paired mother-infant samples during a 14-day study period. The purpose of this study was to develop a field-friendly protocol. Data from 790 mother-infant pairs from nine countries were analyzed using a Markov chain Monte Carlo method with Stan. The data were split into (i) model building (565 pairs) and (ii) design evaluation (225 pairs). EBF classification was based on a previously published cut-off for nonmilk water intake. Classification based on the full design was the reference (gold standard classification). The receiver operating characteristics of parsimonious designs were used to determine an optimal parsimonious classification method. The best two postdose windows (days 7-9 and 13-14) yielded optimal categorization with similar performance in the design evaluation data. This postdose two-sample design provided 95% sensitivity and specificity when compared with the full design.
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Registered trials
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