Evidence map›Paper›PMID 31215016›Full record

ArticleJournal of racial and ethnic health disparities2019

Ethnic Differences in the Association of Depressive Symptoms with Clinical Outcome in Dialysis Patients.

Robbert W Schouten, Gerlinde L Haverkamp, Wim L Loosman, Prataap K Chandie Shaw, Frans J van Ittersum, Yves F C Smets, Louis-Jean Vleming, Friedo W Dekker, Adriaan Honig, Carl E H Siegert

Open access · hybridAbstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Robbert W SchoutenDepartment of Nephrology, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands. r.schouten@olvg.nl.ORCID 0000-0002-6882-8977
Gerlinde L HaverkampDepartment of Nephrology, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands.
Wim L LoosmanDepartment of Nephrology, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands.
Prataap K Chandie ShawDepartment of Nephrology, Haaglanden Medical Center, The Hague, The Netherlands.
Frans J van IttersumDepartment of Nephrology, VU Medical Centre, Amsterdam, The Netherlands.
Yves F C SmetsDepartment of Nephrology, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands.
Louis-Jean VlemingDepartment of Nephrology, Haga Teaching Hospital, The Hague, The Netherlands.
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.
Adriaan HonigDepartment of Psychiatry, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands.
Carl E H SiegertDepartment of Nephrology, Amsterdam UMC (VU University Amsterdam), Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLAmsterdam Neuroscience · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLHaga Hospital · NLLeiden University Medical Center · NLMedisch Centrum Haaglanden · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies show mixed results on the association between depressive symptoms and adverse clinical outcomes in patients on dialysis therapy. Ethnicity may play a role in these heterogeneous results. No studies have investigated the interplay between ethnicity and depressive symptoms on clinical outcome in this patient population. This study aims to examine interaction between ethnicity and depressive symptoms on hospitalization and mortality in dialysis patients.

methodsA multi-ethnic cohort in 10 dialysis centers included 687 dialysis patients between 2012 and 2017, with an average follow-up of 3.2 years. Depressive symptoms were measured using the Beck Depression Inventory. Interaction was assessed by investigating excess risk on an additive scale using both absolute rates and relative risks. Multivariable regression models included demographic, social, and clinical variables.

resultsAdverse outcomes are more pronounced in native patients, compared to immigrant patients. The risk for mortality and hospitalization is considerably higher in native patients compared to immigrants. An excess risk on an additive scale indicates the presence of possible causal interaction.

conclusionsDepressive symptoms are a risk factor for hospitalization and mortality, especially in native dialysis patients. Adverse clinical events associated with depressive symptoms differ among ethnic groups. This differential association could play a role in the conflicting findings in literature. Ethnicity is an important factor when investigating depressive symptoms and clinical outcome in dialysis patients. Future research should focus on the possible mechanisms and pathways involved in these differential associations.

Indexed as

Health Status DisparitiesAdultAgedCohort StudiesDepressionEthnicityFemaleHumansMaleMiddle AgedRenal DialysisTreatment OutcomeDepressionDialysisEthnicityHospitalizationInteractionMortality

Identifiers

PMID31215016
PMCPMC6736895
OpenAlexW2952604127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.