ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2020
Oral health in children with acute lymphoblastic leukaemia: before and after chemotherapy treatment.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chemotherapy-induced oral mucositis in children and adolescents: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Pooled it
- Impact of oral mucositis treated by photobiomodulation protocol on the quality of life of pediatric oncology patients with acute lymphoblastic leukemia.Lasers in medical science · 2026Article
- Targeted Cancer Therapy-on-A-Chip.Advanced healthcare materials · 2024Review
- Oral Mucositis in Adult Cancer Patients Undergoing Chemotherapy: Six-Month On-Treatment Follow-Up.Journal of clinical medicine · 2024Article
- Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Review
- Oral Hygiene Considerations in Adult Patients with Leukemia during a Cycle of Chemotherapy.International journal of environmental research and public health · 2022Article
- The effectiveness of an oral health education and prevention program on the incidence and severity of oral mucositis in pediatric cancer patients: a non-randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Integrated oral care contributes positively to the course of treatment of oncopediatric patients.European journal of pediatrics · 2021Article
- Oral Health, Caries Risk Profiles, and Oral Microbiome of Pediatric Patients with Leukemia Submitted to Chemotherapy.BioMed research international · 2021Article
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6 authors.
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Abstract
aimTo evaluate changes in the oral health status of children under the age of 14 years with acute lymphoblastic leukaemia (ALL) attending a cancer centre before and after chemotherapy treatment. MATERIALS AND
methodsA total of 32 children with ALL without distinction of gender were selected for study. The oral cavity of the patients was evaluated before the induction stage and 17 days later. Clinical evaluation of the submandibular, submental, and cervical lymph nodes was performed. Saliva samples were collected during the early morning hours. Bacterial plaque was assessed by using the Silness and Löe plaque index (SLPI) and gingiva status was evaluated with the gingival Löe and Silness index (GLSI). The WHO toxicity oral scale was used to record the degree of oral mucositis. The resulting data were analysed with McNemar's test, t test (for related samples), and Wilcoxon test.
resultsThere were statistically significant differences for palpable lymph nodes, paleness of oral mucosa, and ecchymoseis, respectively, P ≤ 0.000, P = 0.03, and P = 0.01, with these manifestations decreasing significantly after treatment. Incipient gingivitis had frequencies of 71.9% and 75% before and after treatment, respectively. The mean SLPI score declined significantly from 1.16 ± 0.52 (before treatment) to 0.56 ± 0.36 (after treatment) (P < 0.000); salivary flow increased significantly from 0.54 ± 0.34 to 1.22 ± 1.07 after chemotherapy treatment (P < 0.00). Oral mucositis was present in 24 children (75%) with a 1-2 severity level.
conclusionsAfter chemotherapy treatment, there were changes in the oral conditions of children with ALL. Some manifestations decreased after treatment, whereas in others increased.
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