ArticleOdontology2020
Properties of fucoidans beneficial to oral healthcare.
Article in Odontology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Structure-Function Correlations of Commercial Fucoidan Extracts: Antioxidant, Antiviral, Antifungal, Antibacterial and Prebiotic Activities.Molecules (Basel, Switzerland) · 2026Article
- Marine-Derived Fucose-Containing Carbohydrates: Review of Sources, Structure, and Beneficial Effects on Gastrointestinal Health.Foods (Basel, Switzerland) · 2024Review
- Structural Characterization and Immunoenhancing Properties of Polysaccharide CPTM-P1 fromMolecules (Basel, Switzerland) · 2024Article
- Review
- Healthy Diet and Lifestyle Improve the Gut Microbiota and Help Combat Fungal Infection.Microorganisms · 2023Review
- FTIR Characterization of Sulfated Polysaccharides Obtained fromMarine drugs · 2022Article
- Effect of Brown Algae and Lichen Extracts on the SCOBY Microbiome and Kombucha Properties.Foods (Basel, Switzerland) · 2022Article
- Marine Bioactive Compounds Derived from Macroalgae as New Potential Players in Drug Delivery Systems: A Review.Pharmaceutics · 2022Review
- Recent Advancements and Future Perspectives of Microalgae-Derived Pharmaceuticals.Marine drugs · 2021Review
- Preparation, Antibacterial Activity, and Catalytic Application of Magnetic Graphene Oxide-Fucoidan in the Synthesis of 1,4-Dihydropyridines and Polyhydroquinolines.ChemistryOpen · 2021Article
- Brown Algae Carbohydrates: Structures, Pharmaceutical Properties, and Research Challenges.Marine drugs · 2021Review
- The Impact of Gelatin on the Pharmaceutical Characteristics of Fucoidan Microspheres with Posaconazole.Materials (Basel, Switzerland) · 2021Article
- Modulation of Gene Expression in a Sterile Atopic Dermatitis Model and Inhibition ofDermatopathology (Basel, Switzerland) · 2021Article
- Preparation of Fucoidan-Based Electrospun Nanofibers and Their Interaction With Endothelial Cells.Frontiers in bioengineering and biotechnology · 2021Article
- Mechanisms of Bioactivities of Fucoidan from the Brown SeaweedMarine drugs · 2020Article
- Therapies from Fucoidan: New Developments.Marine drugs · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Fucoidans are sulfated polysaccharides that are found in marine algae and have many useful activities, including antitumor effects, promotion of apoptosis of cancer cells, and antiviral, anti-inflammatory, and antiallergic actions. In oral medicine, several case reports have shown that fucoidan-containing creams and tablets markedly improved recurrent aphthous stomatitis, symptomatic inflamed tongue, and recurrent oral herpes labialis. The aim of this study was to examine the properties of fucoidans for use in oral healthcare. The antimicrobial, anti-adhesion, endotoxin-neutralizing, and cyclooxygenase (COX)-1 and COX-2 inhibitory activities of fucoidans were examined. Four key results were obtained: fucoidans showed strong antimicrobial activity against Candida albicans, Streptococcus mutans, and Porphyromonas gingivalis; significantly inhibited the adhesion of S. mutans to bovine teeth and porcelain; were suggested to bind to and neutralize endotoxin (lipopolysaccharide) in an LAL assay; and showed COX-1 and/or COX-2 inhibitory activity. These results suggested that fucoidans may be useful in the field of oral healthcare.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.