ArticleDiabetologia2019
Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, Scotland.
Article in Diabetologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- The effect of methods used in the management of maternal obesity on pregnancy and birth outcomes: a systematic review with meta-analysis.International journal of obesity (2005) · 2025Pooled it
- Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- The Impact of Maternal Obesity on Offspring Cardiovascular Health: A Systematic Literature Review.Frontiers in endocrinology · 2022Pooled it
- A high-fat, high-sugar diet impairs maternal metabolism throughout pregnancy and lactation in mice.The Journal of physiology · 2026Article
- Placental mitochondrial respiration is inhibited in mice with trophoblast specific AdipoR2 overexpression.Free radical biology & medicine · 2026Article
- Determinants of birth weight in a low- and middle-income country: Sri Lanka Child Growth Cohort (SLCGC).BMJ public health · 2026Article
- Liraglutide-Driven Weight Loss Modulates Placental Remodeling in Obese Pregnancies in Mice.Cells · 2025Article
- Mental health and body mass index in early pregnancy: a secondary analysis of three randomised controlled trials.BMC pregnancy and childbirth · 2025Article
- Article
- I know i'm not meant to 'diet' but is it ok to lose a few pounds while pregnant?: a qualitative analysis of Mumsnet discussion forum posts to understand women's experiences of and views on weight and weight management while living with excess weight during and after pregnancy.BMC pregnancy and childbirth · 2025Article
- Article
- Glucose intolerance as a consequence of hematopoietic stem cell dysfunction in offspring of obese mice.Molecular metabolism · 2024Article
- Growth Restriction in the Offspring of Mothers With Polycystic Ovary Syndrome.JAMA network open · 2024Article
- Neurodevelopmental Programming of Adiposity: Contributions to Obesity Risk.Endocrine reviews · 2024Review
- Childhood obesity from the genes to the epigenome.Frontiers in endocrinology · 2024Review
- Barriers and facilitators for sustainable weight loss in the pre-conception period among Danish women with overweight or obesity - a qualitative study.BMC public health · 2023Article
- Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course.Nature reviews. Cardiology · 2023Review
- Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets.Diabetologia · 2023Article
- Towards a better understanding of diabetes mellitus using organoid models.Nature reviews. Endocrinology · 2023Review
- Dynamic alteration in the gut microbiota and metabolome of Huanjiang mini-pigs during pregnancy.BMC veterinary research · 2022Article
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
aims/hypothesisMaternal obesity in pregnancy is associated with cardiovascular disease and mortality rate in the offspring. We aimed to determine whether maternal obesity is also associated with increased incidence of type 2 and type 1 diabetes in the offspring, independently of maternal diabetes as a candidate mechanistic pathway.
methodsBirth records of 118,201 children from 1950 to 2011 in the Aberdeen Maternity and Neonatal Databank were linked to Scottish Care Information-Diabetes, the national register for diagnosed diabetes in Scotland, to identify incident and prevalent type 1 and type 2 diabetes up to 1 January 2012. Maternal BMI was calculated from height and weight measured at the first antenatal visit. The effect of maternal obesity on offspring outcomes was tested using time-to-event analysis with Cox proportional hazards regression to compare outcomes in offspring of mothers in underweight, overweight or obese categories of BMI, compared with offspring of women with normal BMI.
resultsOffspring of obese (BMI ≥30 kg/m CONCLUSIONS/
interpretationMaternal obesity is associated with increased incidence of type 2 diabetes in the offspring. Evidence-based strategies that reduce obesity among women of reproductive age and that might reduce the incidence of diabetes in their offspring are urgently required.
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