Evidence map›Paper›PMID 31214700›Full record

ArticleBioinformatics (Oxford, England)2019

PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model.

Benjamin S Glicksberg, Boris Oskotsky, Phyllis M Thangaraj, Nicholas Giangreco, Marcus A Badgeley, Kipp W Johnson, Debajyoti Datta, Vivek A Rudrapatna, Nadav Rappoport, Mark M Shervey and 12 more

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Review
  9. VisualSphere: a Web-based Interactive Visualization System for Clinical Research Data.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Benjamin S GlicksbergBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Boris OskotskyBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Phyllis M ThangarajDepartment of Biomedical Informatics, Columbia University, New York, NY, USA.
Nicholas GiangrecoDepartment of Biomedical Informatics, Columbia University, New York, NY, USA.
Marcus A BadgeleyDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Kipp W JohnsonDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Debajyoti DattaBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Vivek A RudrapatnaBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Nadav RappoportBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Mark M SherveyDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Riccardo MiottoDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Theodore C GoldsteinBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Eugenia RutenbergBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Remi FrazierEnterprise Information and Analytics, University of California, San Francisco, San Francisco, CA, USA.
Nelson LeeEnterprise Information and Analytics, University of California, San Francisco, San Francisco, CA, USA.
Sharat IsraniBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.
Rick LarsenEnterprise Information and Analytics, University of California, San Francisco, San Francisco, CA, USA.
Bethany PerchaDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Li LiDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Joel T DudleyDepartments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA.
Nicholas P TatonettiDepartment of Biomedical Informatics, Columbia University, New York, NY, USA.
Atul J ButteBakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Molecular and Cellular Mechanisms in CancerT32CA108462 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOGA, ANDREI · 2004 to 2024
$10.4M
TRAINING PROGRAM IN DISGESTIVE DISEASES AND NUTRITIONT32DK007007 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AVERIL I MA · 1986 to 2026
$6.4M
Precision Pharmacology and Pharmacovigilance: Leveraging AI to address drug safety knowledge gapsR35GM131905 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas P Tatonetti · 2019 to 2026
$3.3M
Data-driven subtyping to find patients with drug interactions leading to strokeF30HL140946 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI THANGARAJ, PHYLLIS MARY · 2018 to 2020
$145k
NCATS NIH HHS UL1 TR001872NCI NIH HHS T32 CA108462NHLBI NIH HHS F30 HL140946NIDDK NIH HHS T32 DK007007NIGMS NIH HHS R35 GM131905
6 · The paper itself

Abstract

motivationElectronic health records (EHRs) are quickly becoming omnipresent in healthcare, but interoperability issues and technical demands limit their use for biomedical and clinical research. Interactive and flexible software that interfaces directly with EHR data structured around a common data model (CDM) could accelerate more EHR-based research by making the data more accessible to researchers who lack computational expertise and/or domain knowledge.

resultsWe present PatientExploreR, an extensible application built on the R/Shiny framework that interfaces with a relational database of EHR data in the Observational Medical Outcomes Partnership CDM format. PatientExploreR produces patient-level interactive and dynamic reports and facilitates visualization of clinical data without any programming required. It allows researchers to easily construct and export patient cohorts from the EHR for analysis with other software. This application could enable easier exploration of patient-level data for physicians and researchers. PatientExploreR can incorporate EHR data from any institution that employs the CDM for users with approved access. The software code is free and open source under the MIT license, enabling institutions to install and users to expand and modify the application for their own purposes. AVAILABILITY AND IMPLEMENTATION: PatientExploreR can be freely obtained from GitHub: https://github.com/BenGlicksberg/PatientExploreR. We provide instructions for how researchers with approved access to their institutional EHR can use this package. We also release an open sandbox server of synthesized patient data for users without EHR access to explore: http://patientexplorer.ucsf.edu. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Electronic Health RecordsSoftwareComputersDatabases, FactualHumansObservational Studies as Topic

Identifiers

PMID31214700
PMCPMC6821222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.