Evidence map›Paper›PMID 31214662›Full record

ArticleJournal of the Endocrine Society2019

Luciferase Reporter Mice for

Elizabeth L Cordonier, Tiemin Liu, Kenji Saito, Siyu S Chen, Yong Xu, Makoto Fukuda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elizabeth L CordonierChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Tiemin LiuDivision of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Kenji SaitoChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Siyu S ChenChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Yong XuChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Makoto FukudaChildren's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.ORCID 0000-0003-0112-9925
Children's Nutrition Research Center at Baylor College of Medicine · USBaylor College of Medicine · USThe University of Texas Southwestern Medical Center · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Consortium for Broad Based Disease Phenotyping of Knockout MiceU54HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI BEAUDET, ARTHUR L., PAYLOR, RICHARD E · 2011 to 2015
$17.0M
Central Role of Gut Hormone GIP in Leptin Resistance and ObesityR01DK104901 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FUKUDA, MAKOTO · 2015 to 2019
$1.6M
The Childrens Nutrition Research Center Training ProgramT32HD071839 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI HAYMOND, MOREY W · 2012 to 2016
$906k
NCI NIH HHS P30 CA125123NHGRI NIH HHS U54 HG006348NICHD NIH HHS T32 HD071839NIDDK NIH HHS R01 DK104901
6 · The paper itself

Abstract

Suppressor of cytokine signaling-3 (SOCS3) is a negative regulator of actions of cytokines and the metabolic hormone leptin. In the hypothalamus, SOCS3 is induced in response to several conditions such as inflammation and high-fat diet feeding, modulates cellular signaling of cytokines and leptin, and mediates the effects of these biological conditions. However, signaling mechanisms controlling hypothalamic

Indexed as

cytokineshypothalamusleptinluciferase reporterSocs3

Identifiers

PMID31214662
PMCPMC6570635
OpenAlexW2942374108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.