Evidence map›Paper›PMID 31214655›Full record

ArticleScience advances2019

Trimethylamine

Bowen Li, Priyesh Jain, Jinrong Ma, Josh K Smith, Zhefan Yuan, Hsiang-Chieh Hung, Yuwei He, Xiaojie Lin, Kan Wu, Jim Pfaendtner and 1 more

Abstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bubble-driven cell detachment.Science advances · 2025
    Article
  11. Article
  12. Free-Standing Supramolecular Pyridine N-Oxide-Silver(I) Metallogels.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Interaction of Grafted PolymericLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bowen LiDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Priyesh JainDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Jinrong MaDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Josh K SmithDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Zhefan YuanDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-4724-6214
Hsiang-Chieh HungDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-7930-3674
Yuwei HeDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Xiaojie LinDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-2911-3685
Kan WuDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Jim PfaendtnerDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-6727-2957
Shaoyi JiangDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Materials that resist nonspecific protein adsorption are needed for many applications. However, few are able to achieve ultralow fouling in complex biological milieu. Zwitterionic polymers emerge as a class of highly effective ultralow fouling materials due to their superhydrophilicity, outperforming other hydrophilic materials such as poly(ethylene glycol). Unfortunately, there are only three major classes of zwitterionic materials based on poly(phosphorylcholine), poly(sulfobetaine), and poly(carboxybetaine) currently available. Inspired by trimethylamine

Indexed as

AdsorptionAnimalsBiocompatible MaterialsBiofoulingCell AdhesionHumansMethylaminesMiceMice, Inbred C57BLMolecular Dynamics SimulationNIH 3T3 CellsPolymersSerum AlbuminSurface Plasmon ResonanceBiocompatible MaterialsMethylaminesPolymersSerum Albumintrimethyloxamine

Identifiers

PMID31214655
PMCPMC6570511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.