Evidence map›Paper›PMID 31214629›Full record

ArticleOpen forum infectious diseases2019

Factors Associated With Ventriculoperitoneal Shunt Placement in Patients With Cryptococcal Meningitis.

John W Baddley, George R Thompson, Kristen O Riley, Mary K Moore, Stephen A Moser, Peter G Pappas

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Critical reviews in microbiology · 2021
    Review
  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John W BaddleyDepartment of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham.
George R ThompsonDepartment of Medical Microbiology and Immunology.
Kristen O RileyDepartment of Neurosurgery, University of Alabama at Birmingham.
Mary K MooreDepartment of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham.
Stephen A MoserDepartment of Pathology, University of Alabama at Birmingham.
Peter G PappasDepartment of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham.
University of Alabama at Birmingham · USBirmingham VA Medical Center · USUniversity of California Davis Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIncreased intracranial pressure (ICP) is an important complication of cryptococcal meningitis (CM) and impacts morbidity and mortality. Factors associated with permanent ventriculoperitoneal (VP) shunt placement are poorly characterized.

methodWe conducted a retrospective cohort study of patients with CM at the University of Alabama at Birmingham from 1996 through 2015. Characteristics of patients at time of CM diagnosis who did and did not receive a VP shunt were compared with use of the 2-group chi-square test or Fisher exact test for categorical variables and the 2-group

resultsOf 422 patients with cryptococcosis, 257 (60.9%) had CM. Mean age was 47.7 years, 71.6% were male, and 44.4% were African American. The most common underlying conditions were HIV (42.4%), solid organ transplantation (29.6%), and corticosteroid use (34.2%). Forty-four (17.1%) received a VP shunt a median of 17 days (range, 1-320 days) post-diagnosis. By multivariable analysis, baseline opening pressure >30 cm H

conclusionsIdentification of factors at time of CM diagnosis associated with need for permanent VP shunt placement may allow for earlier, more aggressive treatment and potentially improve outcomes associated with increased ICP from cryptococcal meningitis.

Indexed as

cryptococcosisCryptococcus neoformansventriculoperitoneal shunt

Identifiers

PMID31214629
PMCPMC6565380
OpenAlexW2945451707

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.