Evidence map›Paper›PMID 31214612›Full record

ArticleBioMed research international2019

Biochemical and Biological Profile of Parotoid Secretion of the Amazonian

Daniel S S de Medeiros, Tiago B Rego, Ana P de A Dos Santos, Adriana S Pontes, Leandro S Moreira-Dill, Najla B Matos, Juliana P Zuliani, Rodrigo G Stábeli, Carolina B G Teles, Andreimar M Soares and 6 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Antimalarial efficacy ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  4. Biochemical Characterisation andTropical life sciences research · 2024
    Article
  5. Review
  6. Article
  7. Uncovering the antimalarial potential of toad venoms through a bioassay-guided fractionation process.International journal for parasitology. Drugs and drug resistance · 2022
    Article
  8. Vasoconstrictor and hemodynamic effects of a methanolic extract from Rhinella marina toad poison.Toxicon : official journal of the International Society on Toxinology · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Daniel S S de MedeirosCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.ORCID 0000-0002-6644-4638
Tiago B RegoCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.ORCID 0000-0001-6051-1468
Ana P de A Dos SantosCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Adriana S PontesLaboratório de Imunologia Aplicada à Saúde, FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Leandro S Moreira-DillCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.ORCID 0000-0003-2977-0001
Najla B MatosInstituto Nacional de Epidemiologia na Amazônia Ocidental, Porto Velho, 76812-245, Brazil.
Juliana P ZulianiInstituto Nacional de Epidemiologia na Amazônia Ocidental, Porto Velho, 76812-245, Brazil.
Rodrigo G StábeliCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Carolina B G TelesPlataforma de Bioensaios de Malária e Leishmaniose (PBML), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Andreimar M SoaresCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Angelo R de M SperottoLaboratório de Genética Toxicológica, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, 90050-170, Brazil.
Dinara J MouraLaboratório de Genética Toxicológica, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, 90050-170, Brazil.
Jenifer SaffiLaboratório de Genética Toxicológica, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, 90050-170, Brazil.
Cleópatra Alves da Silva CaldeiraCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.
Daniel Carvalho PimentaLaboratório de Bioquímica e Biofísica, Instituto Butantan, Avenida Vital Brazil, 1500, 05503-900 Sao Paulo, SP, Brazil.ORCID 0000-0003-2406-0860
Leonardo A CalderonCentro de Estudo de Biomoléculas Aplicadas à Saúde (CEBio), FIOCRUZ-Rondônia, Porto Velho, 76812-245, Brazil.ORCID 0000-0003-2669-092X
Universidade Federal de Rondônia · BRFundação Oswaldo Cruz · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRInstituto Butantan · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin secretions of frogs have a high chemical complexity. They have diverse types of biomolecules, such as proteins, peptides, biogenic amines, and alkaloids. These compounds protect amphibians' skin against growth of bacteria, fungi, and protozoa and participate in defense system against attack from predators. Therewith, this work performed biochemical and biological profile of macroglands parotoid secretion from cane toad. For poison analysis, we performed molecular exclusion and reverse phase chromatography, electrophoresis, and mass spectrometry. Antimicrobial, antiplasmodial, leishmanicidal, cytotoxicity, genotoxicity, and inflammatory activity of crude and/or fractions of

Indexed as

Anti-Bacterial AgentsBufanolidesAnimalsBufo marinusParotid GlandPseudomonas aeruginosaSkinStaphylococcus aureusAnti-Bacterial AgentsBufanolidesdesacetylcinobufagin

Identifiers

PMID31214612
PMCPMC6535847
OpenAlexW2916544833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.