Evidence map›Paper›PMID 31214598›Full record

ReviewFrontiers in cardiovascular medicine2019

Effects of Exercise to Improve Cardiovascular Health.

Kelsey Pinckard, Kedryn K Baskin, Kristin I Stanford

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 219 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
219citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

219 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  18. LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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159 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kelsey PinckardDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Kedryn K BaskinDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Kristin I StanfordDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, United States.

Funding

A Novel Role for Brown Adipose Tissue Enhance Heart Function and MetabolismR01HL138738 · NHLBI · OHIO STATE UNIVERSITY · PI STANFORD, KRISTIN I · 2017 to 2021
$2.3M
Cardiomyokines regulate inter-organ communication and metabolismK01DK116916 · NIDDK · OHIO STATE UNIVERSITY · PI BASKIN, KEDRYN K · 2018 to 2021
$428k
NHLBI NIH HHS R01 HL138738NIDDK NIH HHS K01 DK116916
6 · The paper itself

Abstract

Obesity is a complex disease that affects whole body metabolism and is associated with an increased risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D). Physical exercise results in numerous health benefits and is an important tool to combat obesity and its co-morbidities, including cardiovascular disease. Exercise prevents both the onset and development of cardiovascular disease and is an important therapeutic tool to improve outcomes for patients with cardiovascular disease. Some benefits of exercise include enhanced mitochondrial function, restoration and improvement of vasculature, and the release of myokines from skeletal muscle that preserve or augment cardiovascular function. In this review we will discuss the mechanisms through which exercise promotes cardiovascular health.

Indexed as

cardiovascularexercisemyokinesobesity—complicationstype 2 diabetes

Identifiers

PMID31214598
PMCPMC6557987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.