ReviewFrontiers in bioengineering and biotechnology2019
Biomechanical Investigation of Disturbed Hemodynamics-Induced Tissue Degeneration in Abdominal Aortic Aneurysms Using Computational and Experimental Techniques.
Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 101 citations in OpenAlex.
- Integrated Assessment of Wall Shear Stress-Related Hemodynamic Parameters in Abdominal Aortic Aneurysms: A Retrospective Cross-Sectional Study on Ruptured Cases.International journal for numerical methods in biomedical engineering · 2026Article
- Article
- Review
- Finite Element Modeling in Left Ventricular Cardiac Biomechanics: From Computational Tool to Clinical Practice.Bioengineering (Basel, Switzerland) · 2025Review
- Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD.Medical & biological engineering & computing · 2025Article
- Left atrial wall shear stress correlates with fibrosis in patients with atrial fibrillation.Nature cardiovascular research · 2025Observational
- Modeling Techniques and Boundary Conditions in Abdominal Aortic Aneurysm Analysis: Latest Developments in Simulation and Integration of Machine Learning and Data-Driven Approaches.Bioengineering (Basel, Switzerland) · 2025Review
- Integrated multidisciplinary approach to aneurysm hemodynamic analysis: numerical simulation,Frontiers in bioengineering and biotechnology · 2025Review
- An evidence update to explore molecular targets and protective mechanisms of apigenin against abdominal aortic aneurysms based on network pharmacology and experimental validation.Molecular diversity · 2024Article
- On the feasibility of ultrasound Doppler-based personalized hemodynamic modeling of the abdominal aorta.Biomedical engineering online · 2024Article
- The Effect of Mechanical Circulatory Support on Blood Flow in the Ascending Aorta: A Combined Experimental and Computational Study.Bioengineering (Basel, Switzerland) · 2024Article
- Enhancing the implantation of mechanical circulatory support devices using computational simulations.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- A hemodynamic analysis of energy loss in abdominal aortic aneurysm using three-dimension idealized model.Frontiers in physiology · 2024Article
- Bio-inspired microfluidics: A review.Biomicrofluidics · 2023Review
- Haemodynamic changes in visceral hybrid repairs of type III and type V thoracoabdominal aortic aneurysms.Scientific reports · 2023Article
- The Impact of a Limited Field-of-View on Computed Hemodynamics in Abdominal Aortic Aneurysms: Evaluating the Feasibility of Completing Ultrasound Segmentations with Parametric Geometries.Annals of biomedical engineering · 2023Article
- Effect of Intraluminal Thrombus Burden on the Risk of Abdominal Aortic Aneurysm Rupture.Journal of cardiovascular development and disease · 2023Article
- Impact of spatial and temporal stability of flow vortices on vascular endothelial cells.Biomechanics and modeling in mechanobiology · 2023Article
- The study on the impact of AAA wall motion on the hemodynamics based on 4D CT image data.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal aortic aneurysm (AAA) is the dilatation of the aorta beyond 50% of the normal vessel diameter. It is reported that 4-8% of men and 0.5-1% of women above 50 years of age bear an AAA and it accounts for ~15,000 deaths per year in the United States alone. If left untreated, AAA might gradually expand until rupture; the most catastrophic complication of the aneurysmal disease that is accompanied by a striking overall mortality of 80%. The precise mechanisms leading to AAA rupture remains unclear. Therefore, characterization of disturbed hemodynamics within AAAs will help to understand the mechanobiological development of the condition which will contribute to novel therapies for the condition. Due to geometrical complexities, it is challenging to directly quantify disturbed flows for AAAs clinically. Two other approaches for this investigation are computational modeling and experimental flow measurement. In computational modeling, the problem is first defined mathematically, and the solution is approximated with numerical techniques to get characteristics of flow. In experimental flow measurement, once the setup providing physiological flow pattern in a phantom geometry is constructed, velocity measurement system such as particle image velocimetry (PIV) enables characterization of the flow. We witness increasing number of applications of these complimentary approaches for AAA investigations in recent years. In this paper, we outline the details of computational modeling procedures and experimental settings and summarize important findings from recent studies, which will help researchers for AAA investigations and rupture mechanics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.