Evidence map›Paper›PMID 31214576›Full record

ReviewFrontiers in chemistry2019

Electric and Electrochemical Microfluidic Devices for Cell Analysis.

Kaoru Hiramoto, Kosuke Ino, Yuji Nashimoto, Kentaro Ito, Hitoshi Shiku

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  3. Review
  4. Article
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kaoru HiramotoGraduate School of Environmental Studies, Tohoku University, Sendai, Japan.
Kosuke InoGraduate School of Engineering, Tohoku University, Sendai, Japan.
Yuji NashimotoGraduate School of Engineering, Tohoku University, Sendai, Japan.
Kentaro ItoGraduate School of Environmental Studies, Tohoku University, Sendai, Japan.
Hitoshi ShikuGraduate School of Engineering, Tohoku University, Sendai, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidic devices are widely used for cell analysis, including applications for single-cell analysis, healthcare, environmental monitoring, and organs-on-a-chip that mimic organs in microfluidics. Moreover, to enable high-throughput cell analysis, real-time monitoring, and non-invasive cell assays, electric and electrochemical systems have been incorporated into microfluidic devices. In this mini-review, we summarize recent advances in these systems, with applications from single cells to three-dimensional cultured cells and organs-on-a-chip. First, we summarize microfluidic devices combined with dielectrophoresis, electrophoresis, and electrowetting-on-a-dielectric for cell manipulation. Next, we review electric and electrochemical assays of cells to determine chemical section activity, and oxygen and glucose consumption activity, among other applications. In addition, we discuss recent devices designed for the electric and electrochemical collection of cell components from cells. Finally, we highlight the future directions of research in this field and their application prospects.

Indexed as

cell analysiscell manipulationelectric deviceselectrochemical devicesmicrofluidic devicesorgans-on-a-chip

Identifiers

PMID31214576
PMCPMC6557978
OpenAlexW2946093271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.