ArticleFrontiers in chemistry2019
Discovery of Potential Anti-infective Therapy Targeting Glutamine Synthetase in
Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Bacillibactin, a PotentialInternational journal of molecular sciences · 2025Article
- In Vitro Evaluation of the Antibacterial Effect and Influence on the Bacterial Biofilm Formation of Glutamic Acid and Some Structural Analogues.Antibiotics (Basel, Switzerland) · 2025Article
- Article
- CD-g-CS nanoparticles for enhanced antibiotic treatment of Staphylococcus xylosus infection.Microbial biotechnology · 2022Article
- Comparative Proteomic Analysis Reveals Antibacterial Mechanism ofInfection and drug resistance · 2022Article
- UsingFrontiers in pharmacology · 2022Review
- Potential Antimicrobial Activity of Galloyl-Flavonoid Glycosides FromFrontiers in microbiology · 2021Article
- A Label-Free Cellular Proteomics Approach to Decipher the Antifungal Action of DiMIQ, a Potent Indolo[2,3-International journal of molecular sciences · 2020Article
- Inactivation of Glutamine Synthetase-Coding GeneFrontiers in microbiology · 2020Article
- The Active Ingredients Identification and Antidiarrheal Mechanism Analysis ofFrontiers in pharmacology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential roles in most biological growth and biofilm formation, suggesting that GS may be used as a promising target for antibacterial therapy. We asked whether a GS inhibitor could be found as an anti-infective agent of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.