Evidence map›Paper›PMID 31214175›Full record

ReviewFrontiers in immunology2019

Commensal Bacteria: An Emerging Player in Defense Against Respiratory Pathogens.

Rabia Khan, Fernanda Cristina Petersen, Sudhanshu Shekhar

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Review
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  4. Observational
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  9. Article
  10. Upper Respiratory Microbiome in Vasculitis.Rheumatic diseases clinics of North America · 2025
    Review
  11. Article
  12. Microbiome and Communication Disorders: A Tutorial for Clinicians.Journal of speech, language, and hearing research : JSLHR · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Article
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  18. Article
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rabia KhanFaculty of Dentistry, Institute of Oral Biology, University of Oslo, Oslo, Norway.
Fernanda Cristina PetersenFaculty of Dentistry, Institute of Oral Biology, University of Oslo, Oslo, Norway.
Sudhanshu ShekharFaculty of Dentistry, Institute of Oral Biology, University of Oslo, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A diverse community of trillions of commensal bacteria inhabits mucosal and epidermal surfaces in humans and plays an important role in defense against pathogens, including respiratory pathogens. Commensal bacteria act on the host's immune system to induce protective responses that prevent colonization and invasion by pathogens. On the other hand, these bacteria can directly inhibit the growth of respiratory pathogens by producing antimicrobial products/signals and competing for nutrients and adhesion sites. Such mechanisms preserve the niche for commensal bacteria and support the host in containing respiratory infections. Herein, we discuss current evidence on the role of commensal bacteria in conferring protection against respiratory pathogens and the underlying mechanisms by which these bacteria do so. A deeper knowledge of how commensal bacteria interact with the host and pathogens might provide new insights that are poised to aid in the development of vaccines and therapeutics that target infectious diseases.

Indexed as

Bacterial Physiological PhenomenaHost-Pathogen InteractionsMicrobiotaAnimalsDisease Models, AnimalHumansRespiratory Tract Infectionscommensalhostlungspathogenvaccine

Identifiers

PMID31214175
PMCPMC6554327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.