Evidence map›Paper›PMID 31214166›Full record

ArticleFrontiers in immunology2019

Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (

Verónica Calonga-Solís, Danielle Malheiros, Marcia Holsbach Beltrame, Luciana de Brito Vargas, Renata Montoro Dourado, Hellen Caroline Issler, Roseli Wassem, Maria Luiza Petzl-Erler, Danillo G Augusto

Abstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Immunoglobulin allotypes andJournal of Alzheimer's disease : JAD · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. B cell tolerance and autoimmunity: Lessons from repertoires.The Journal of experimental medicine · 2024
    Review
  10. Article
  11. Identification of IgG1 and IgG3 Allotypes by PCR and Sanger Sequencing.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Constant domain polymorphisms influence monoclonal antibody stability and dynamics.Protein science : a publication of the Protein Society · 2023
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Verónica Calonga-SolísLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Danielle MalheirosLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Marcia Holsbach BeltrameLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Luciana de Brito VargasLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Renata Montoro DouradoLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Hellen Caroline IsslerLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Roseli WassemLaboratório de Interação Planta-Bactéria, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Maria Luiza Petzl-ErlerLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.
Danillo G AugustoLaboratório de Genética Molecular Humana, Departamento de Genética, Universidade Federal do Paraná, Curitiba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even though immunoglobulins are critical for immune responses and human survival, the diversity of the immunoglobulin heavy chain gene (

Indexed as

AllelesGene ConversionGenes, Immunoglobulin Heavy ChainGenetics, PopulationGenetic VariationSelection, GeneticBrazilGene FrequencyGeographyHaplotypesHumansImmunoglobulin gamma-ChainsImmunoglobulin Gm AllotypesLinkage DisequilibriumPolymorphism, Single NucleotideImmunoglobulin gamma-ChainsImmunoglobulin Gm AllotypesDNA sequencinggenetic diversityIGHG genesimmunoglobulin heavy chainmolecular characterizationpopulations

Identifiers

PMID31214166
PMCPMC6558194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.