Evidence map›Paper›PMID 31214131›Full record

ArticleFrontiers in microbiology2019

Blood Microbial Communities During Pregnancy Are Associated With Preterm Birth.

Young-Ah You, Jae Young Yoo, Eun Jin Kwon, Young Ju Kim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Pathological Alterations in Human Blood Microbiome-An Updated Review.International journal of molecular sciences · 2025
    Review
  4. The Microbiome and Metabolic Dysfunction-Associated Steatotic Liver Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Oral microbiome and preterm birth.Frontiers in medicine · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Role of Genital Mycoplasmas in Preterm Labor.Journal of reproduction & infertility
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Young-Ah YouDepartment of Obstetrics and Gynecology, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, South Korea.
Jae Young YooDepartment of Obstetrics and Gynecology, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, South Korea.
Eun Jin KwonDepartment of Obstetrics and Gynecology, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, South Korea.
Young Ju KimDepartment of Obstetrics and Gynecology, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, South Korea.
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial infection of the placenta, amniotic fluid, vaginal canal, and oral cavity is known to significantly contribute to preterm birth (PTB). Although microbes can be translocated into the blood, little is known regarding the blood microbiota during pregnancy. To assess changes in the microbiome during pregnancy, blood samples were obtained 2 or 3 times during pregnancy from a cohort of 45 pregnant women enrolled between 2008 and 2010. To analyze the association with PTB, we conducted a case-control study involving 41 pregnant women upon admission for preterm labor and rupture of membrane (20 with term delivery; 21 with PTB). Bacterial diversity was assessed in number and composition between the first, second, and third trimesters in term delivered women according to 16S rRNA gene amplicon sequencing, and data were analyzed using Quantitative Insight Into Microbial Ecology (QIIME). Taxonomy was assigned using the GreenGenes 8.15.13 database. Dominant microorganisms at the phylum level in all pregnant women were identified as

Indexed as

16S rRNA gene sequencingblood microbiotamicrobiomepregnancypreterm birth

Identifiers

PMID31214131
PMCPMC6558066
OpenAlexW2948924956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.