Evidence map›Paper›PMID 31214115›Full record

ArticleFrontiers in endocrinology2019

Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis.

Jorge Espinoza-Derout, Xuesi M Shao, Emmanuel Bankole, Kamrul M Hasan, Norma Mtume, Yanjun Liu, Amiya P Sinha-Hikim, Theodore C Friedman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Cigarette smoking and alcohol-related liver disease.Liver research (Beijing, China) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Electronic Cigarette Use and the Risk of Cardiovascular Diseases.Frontiers in cardiovascular medicine · 2022
    Review
  15. Article
  16. Review
  17. Review
  18. Neurotoxicity of e-cigarettes.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jorge Espinoza-DeroutDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Xuesi M ShaoDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Emmanuel BankoleDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Kamrul M HasanDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Norma MtumeDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Yanjun LiuDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Amiya P Sinha-HikimDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Theodore C FriedmanDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, CA, United States.
Charles R. Drew University of Medicine and Science · USUniversity of California, Los Angeles · US

Funding

Workshop for Junior Biostatisticians in Health ResearchU54MD007598 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI Ali Andalibi, Jose A Torres-Ruiz · 2012 to 2026
$60.0M
Drew MIDARP (Infrastructure in Drug Abuse Research)R24DA017298 · NIDA · CHARLES R. DREW UNIVERSITY OF MED &SCI · PI FRIEDMAN, THEODORE C · 2004 to 2018
$5.0M
Maternal inhaled nicotine leads to aberrant development of hypertensive phenotypeR01HL135623 · NHLBI · LOMA LINDA UNIVERSITY · PI SHAO, XUESI MAX, XIAO, DALIAO · 2017 to 2021
$2.3M
The Role of Adipose H6PDH in Type 2 Diabetes and ObesitySC1DK104821 · NIDDK · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI LIU, YANJUN · 2014 to 2017
$1.3M
Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette usersR42DA044788 · NIDA · AUTOMATE SCIENTIFIC, INC. · PI KEWEKORDES, JOSEF, SHAO, XUESI MAX · 2019 to 2020
$884k
Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette usersR41DA044788 · NIDA · AUTOMATE SCIENTIFIC, INC. · PI KEWEKORDES, JOSEF, SHAO, XUESI MAX · 2018 to 2018
$150k
NHLBI NIH HHS R01 HL135623NIDA NIH HHS R24 DA017298NIDA NIH HHS R41 DA044788NIDA NIH HHS R42 DA044788NIDDK NIH HHS SC1 DK104821NIMHD NIH HHS U54 MD007598
6 · The paper itself

Abstract

The prevalence of electronic cigarette (e-cigarettes) use has rapidly increased worldwide. Use of tobacco products has been associated with DNA damage and metabolic syndrome. Using Apolipoprotein E knockout (ApoE

Indexed as

DNA damagehepatic metabolismmitochondriaNAD+reactive oxygen species

Identifiers

PMID31214115
PMCPMC6558099
OpenAlexW2948687430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.