Evidence map›Paper›PMID 31213888›Full record

ArticleJournal of pain research2019

Pharmacokinetics, safety, and efficacy of tapentadol oral solution for treating moderate to severe pain in pediatric patients.

Derek Muse, Eva Tarau, Claudia Lefeber, Melanie Sohns, Martin Brett, Jutta Goldberg, Ronald Rosenburg

Registry-linked trialAbstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01729728 (Open-label Evaluation of the Pharmacokinetic Profile, Safety, and Efficacy of Tapentadol Oral Solution for the Treatment of Post-surgical Pain in Children and Adolescents Aged From 2 Years to Less Than 18 Years.), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01729728 phase2completednot on this map

Open-label Evaluation of the Pharmacokinetic Profile, Safety, and Efficacy of Tapentadol Oral Solution for the Treatment of Post-surgical Pain in Children and Adolescents Aged From 2 Years to Less Than 18 Years.

TypeinterventionalSponsorGrünenthal GmbHRan2012 to 2014Enrolled86ConditionsPostoperative Pain, Acute PainArmsTapentadol
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Derek MuseJean Brown Research, Salt Lake City, UT, USA.
Eva TarauGrünenthal USA Inc., Overland Park, KS, USA.
Claudia LefeberGrünenthal GmbH, Aachen, Germany.
Melanie SohnsGrünenthal GmbH, Aachen, Germany.
Martin BrettGrünenthal GmbH, Aachen, Germany.
Jutta GoldbergGrünenthal GmbH, Aachen, Germany.
Ronald RosenburgGrünenthal GmbH, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

analgesicsmoderate to severe painopioid receptorspediatric pain managementtapentadol

Identifiers

PMID31213888
PMCPMC6549717

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.