Evidence map›Paper›PMID 31213793›Full record

ReviewInternational journal of chronic obstructive pulmonary disease2019

Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions.

Nicola A Hanania, Denis E O'Donnell

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06477367 (The Effect of Video-Based Breathing Exercises Taught to COPD Patients on Dyspnea Severity, Activity Level, and Sleep Quality), which is not on this map. Cited by 77 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06477367 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of Video-Based Breathing Exercises Taught to COPD Patients on Dyspnea Severity, Activity Level, and Sleep Quality

TypeinterventionalSponsorBartın UnıversityRan2024 to 2026Enrolled60ConditionsPulmonary Disease, Chronic ObstructiveArmsVideo-Based Breathing Exercises
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
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  6. COPD-Related Anxiety: A Systematic Review of Patient Perspectives.International journal of chronic obstructive pulmonary disease · 2023
    Pooled it
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  20. Kinesiophobia in Patients with Chronic Obstructive Pulmonary Disease: A Concept Analysis.International journal of chronic obstructive pulmonary disease · 2026
    Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicola A HananiaDepartment of Medicine, Section of Pulmonary and Critical Care, Baylor College of Medicine, Houston, TX, USA.
Denis E O'DonnellDivision of Respirology, Department of Medicine, Queen's University, Kingston, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyspnea is a distressing, debilitating, and near-ubiquitous symptom affecting patients with COPD. In addition to the functional consequences of dyspnea, which include activity limitation and reduced exercise tolerance, it is important to consider its psychological impact on patients with COPD, such as onset of depression or anxiety. Moreover, the anticipation of dyspnea itself can have a significant effect on patients' emotions and behavior, with patients frequently self-limiting physical activity to avoid what has become the hallmark symptom of COPD. Dyspnea is, therefore, a key target for COPD treatments. Pharmacologic treatments can optimize respiratory mechanics, provide symptom relief, and reduce patients' increased inspiratory neural drive to breathe. However, it is important to acknowledge the value of non-pharmacologic interventions, such as pulmonary rehabilitation and patient self-management education, which have proven to be invaluable tools for targeting the affective components of dyspnea. Furthermore, it is important to encourage maintenance of physical activity to optimize long-term patient outcomes. Here, we review the physiological and psychological consequences of activity-related dyspnea in COPD, assess the efficacy of modern management strategies in improving this common respiratory symptom, and discuss key unmet clinical and research needs that warrant further immediate attention.

Indexed as

Cost of IllnessExerciseExercise ToleranceAdaptation, PsychologicalAnimalsBronchodilator AgentsDyspneaHealth Services Needs and DemandHealth StatusHumansLungMental HealthNeeds AssessmentPulmonary Disease, Chronic ObstructiveRespiratory TherapyRisk FactorsBronchodilator Agentschronic obstructive pulmonary diseasedyspneamanagementphysiologypsychology

Identifiers

PMID31213793
PMCPMC6538882

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.