Evidence map›Paper›PMID 31213637›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Maternal obesity and cesarean section delivery: additional risk factors for neonatal hypoglycemia?

Daria Turner, Carmen Monthé-Drèze, Sara Cherkerzian, Katherine Gregory, Sarbattama Sen

Registry-linked trialAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05081804 (The Effect of Enhanced Recovery After Surgery), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05081804 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Effect of Enhanced Recovery After Surgery (ERAS) for Cesarean Section on Neonatal Blood Glucose - A Randomized Equivalency Trial

TypeinterventionalSponsorUniversity of ArizonaRan2021 to 2024Enrolled216ConditionsEnhanced Recovery After Surgery, Cesarean SectionArmsCarbohydrate Preoperative Drink
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  10. Review
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  12. Cerebral Effects of Neonatal Dysglycemia.Clinics in perinatology · 2022
    Review
  13. Article
  14. Article
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  16. Article
  17. Type of feeding provided with dextrose gel impacts hypoglycemia outcomes: comparing donor milk, formula, and breastfeeding.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
  18. Article
  19. Placental function in maternal obesity.Clinical science (London, England : 1979) · 2020
    Review
  20. Association of maternal obesity and neonatal hypoxic ischemic encephalopathy.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daria TurnerDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Brigham and Women's Hospital, Boston, MA, USA.
Carmen Monthé-DrèzeDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Brigham and Women's Hospital, Boston, MA, USA.
Sara CherkerzianDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Brigham and Women's Hospital, Boston, MA, USA.
Katherine GregoryDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Brigham and Women's Hospital, Boston, MA, USA.
Sarbattama SenDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Brigham and Women's Hospital, Boston, MA, USA. Ssen2@bwh.harvard.edu.
Brigham and Women's Hospital · USHarvard University · US

Funding

BMI-Based Prenatal Vitamins To Ameliorate Oxidative Stress In Obese PregnancyK23HD074648 · NICHD · TUFTS MEDICAL CENTER · PI SEN, SARBATTAMA · 2013 to 2017
$814k
NICHD NIH HHS K23 HD074648
6 · The paper itself

Abstract

objectivesTo determine (1) whether higher maternal body mass index (BMI) and Cesarean (C) Section mode of delivery are associated with neonatal hypoglycemia (NH) and (2) whether timing of NH onset differs by risk factors. STUDY

designRetrospective cohort study (n = 4602) to determine the odds of NH, NH requiring IV dextrose and timing of NH onset among infants with established and plausible (BMI and C-section) risk factors.

resultInfants born to class III obese mothers had higher odds of NH (OR 1.3, 95% CI 1.0-1.8) and of requiring IV dextrose (OR 2.2, 95% CI 1.2-3.9). Infants born via C-section had higher odds of requiring IV dextrose (OR 1.4, 95% CI 1.1-1.9). Infants who were delivered to high BMI mothers and by C-section developed NH earlier than the reference group.

conclusionDetermining the predictors and timing of NH onset may help develop tailored evaluation and management strategies for at-risk neonates.

Indexed as

Pregnancy ComplicationsBody Mass IndexCesarean SectionCongenital AbnormalitiesFemaleHumansHypoglycemiaInfant, NewbornInfant, Newborn, DiseasesMaleMothersObesityPregnancyRetrospective StudiesRisk Factors

Identifiers

PMID31213637
PMCPMC6660417
OpenAlexW2952855331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.