ArticleScientific reports2019
LC/MS analysis and deep sequencing reveal the accurate RNA composition in the HIV-1 virion.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- tRNA modifications in viral replication.The Journal of biological chemistry · 2026Review
- Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection.Cell reports · 2026Article
- Mechanisms of APOBEC3 Packaging into HIV-1.Viruses · 2026Review
- Exploring RNA modifications in infectious non-coding circular RNAs.RNA biology · 2025Article
- Methylation modifications in tRNA and associated disorders: Current research and potential therapeutic targets.Cell proliferation · 2024Review
- Interactome of the HIV-1 proteome and human host RNA.EMBO reports · 2024Article
- May I Help You with Your Coat? HIV-1 Capsid Uncoating and Reverse Transcription.International journal of molecular sciences · 2024Review
- HIV-1 Infection Reduces NAD Capping of Host Cell snRNA and snoRNA.ACS chemical biology · 2024Article
- Article
- NNature communications · 2024Article
- Structural and computational studies of HIV-1 RNA.RNA biology · 2024Review
- Rewiring of the Host Cell Metabolome and Lipidome during Lytic Gammaherpesvirus Infection Is Essential for Infectious-Virus Production.Journal of virology · 2023Article
- Honeybee Iflaviruses Pack Specific tRNA Fragments from Host Cells in Their Virions.Chembiochem : a European journal of chemical biology · 2022Article
- The Role of RNA Modification in HIV-1 Infection.International journal of molecular sciences · 2022Review
- Control of animal virus replication by RNA adenosine methylation.Advances in virus research · 2022Review
- Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication.Nucleic acids research · 2021Article
- Broad-range RNA modification analysis of complex biological samples using rapid C18-UPLC-MS.RNA biology · 2021Article
- HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators.ACS omega · 2021Article
- Review
- MODOMICS: An Operational Guide to the Use of the RNA Modification Pathways Database.Methods in molecular biology (Clifton, N.J.) · 2021Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanism of action of various viruses has been the primary focus of many studies. Yet, the data on RNA modifications in any type of virus are scarce. Methods for the sensitive analysis of RNA modifications have been developed only recently and they have not been applied to viruses. In particular, the RNA composition of HIV-1 virions has never been determined with sufficiently exact methods. Here, we reveal that the RNA of HIV-1 virions contains surprisingly high amount of the 1-methyladenosine. We are the first to use a liquid chromatography-mass spectrometry analysis (LC/MS) of virion RNA, which we combined with m
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