Evidence map›Paper›PMID 31213562›Full record

ArticlemBio2019

Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host.

Brad Griesenauer, Tuan M Tran, Kate R Fortney, Diane M Janowicz, Paula Johnson, Hongyu Gao, Stephen Barnes, Landon S Wilson, Yunlong Liu, Stanley M Spinola

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Molecular pathogenesis ofMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  2. Recent advances in diagnostic technologies for postoperative central nervous system infections: a review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  3. AInfection and immunity · 2024
    Article
  4. Formate production is dispensable forInfection and immunity · 2023
    Article
  5. Microbiology spectrum · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Microbial extracellular RNAs and their roles in human diseases.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Brad GriesenauerDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Tuan M TranDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kate R FortneyDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Diane M JanowiczDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Paula JohnsonDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Hongyu GaoDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Stephen BarnesDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Landon S WilsonTargeted Metabolomics and Proteomics Laboratory, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yunlong LiuDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Stanley M SpinolaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA sspinola@iu.edu.
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · USTarget (United States) · USUniversity of Alabama at Birmingham · US

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Training in STIs and infections of global health significanceT32AI007637 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WOOLS-KALOUSTIAN, KARA KAY · 2001 to 2020
$3.4M
The Role of the Skin Microbiome in Cutaneous Ulcers in Children in the TropicsR01AI134727 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SPINOLA, STANLEY M. · 2018 to 2020
$1.9M
5500 Q-Trap Mass SpectrometerS10RR027822 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARNES, STEPHEN · 2010 to 2010
$469k
NCATS NIH HHS UL1 TR001108NCRR NIH HHS S10 RR027822NIAID NIH HHS R01 AI134727NIAID NIH HHS T32 AI007637
6 · The paper itself

Abstract

A major gap in understanding infectious diseases is the lack of information about molecular interaction networks between pathogens and the human host.

Indexed as

Gene Regulatory NetworksMetabolomeAdultAnaerobiosisAscorbic AcidBacterial ProteinsChancroidFemaleGene Expression ProfilingHaemophilus ducreyiHost-Pathogen InteractionsHumansMaleMetabolomicsMiddle AgedRNA-SeqAscorbic AcidBacterial Proteinsdual RNA-seqHaemophilus ducreyihuman infection modelinteractomemetabolome

Identifiers

PMID31213562
PMCPMC6581864
OpenAlexW2949440915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.